Nurse Jackie: The First Season Two Trailer

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Nurse Jackie returns for another shift on Showtime on March 22.

While the first season concluded on a dour note (Eddie discovered Jackie's family and our favorite troubled nurse turned to more drugs in response), the scenes depicted in the trailer below actually seem funnier than ever.

Be sure to wait until the very last line, as Jackie explains what it's like to think of Zoey having sex...

[video url="http://www.tvfanatic.com/videos/season-two-trailer/" title="Season Two Trailer"] [/video]

What else can fans expect on season two? A "new gear of gay," according to the series creator.

Matt Richenthal is the Editor in Chief of TV Fanatic. Follow him on Twitter and on Google+.

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Nurse Jackie Quotes

Don't ever say "ta-da." The only people that say "ta-da" are magicians or idiots.

Jackie Peyton

Percoset should never be crushed and chewed, unless you want it to hit your system like a bolt of lightening. Which is only a problem if you're afraid of lightening.

Jackie Peyton