One of the burning questions as Season Six of Grey's Anatomy winds down is who Mark Sloan hooks up with - an incident that may end up driving him back to Lexie.

We know for a fact that Teddy, who McSteamy quasi-dated, is not involved in this scenario. We also know it isn't Bailey or Meredith, because ... well, come on, right?

There are some other long shots out there (Cristina, Arizona), because you just never know, but in all likelihood we see it narrowing down to three primary options:

Callie Torres or one of the two Mercy West transplants.

Callie's relationship with Arizona seems a likely candidate for this May's big breakup, and we know her history with Mark. Reed and April? They're ... well, available.

Who do you think it is? Vote and comment below ...

Mark Sloan is totally going to get with ...

Steve Marsi is the Managing Editor of TV Fanatic. Follow him on Google+ or email him here.