People magazine's annual Sexiest Man Alive honor is a huge deal.

For whatever reason, fans buzz about it, celebrity gossip sites post about it, and even the stars themselves take it personally when they feel they've been snubbed.

Here's our very own Patrick Dempsey, for example, reacting to the announcement that it went to Ryan Reynolds - Ryan Reynolds! - in the heat of the moment:

Steve Marsi is the Managing Editor of TV Fanatic. Follow him on Google+ or email him here.