Grey's Anatomy Sneak Peek: Sister, Sister ...

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A new clip from this week's Grey's Anatomy features two sisters (guest stars Nia Vardalos and Peri Gilpin) admitted to the hospital for a liver transplant and engaging with Meredith prior to the operation.

Vardalos' character is the one with liver failure, but it's Gilpin's who commands the attention. Despite the fact that her own sister appears to be in dire medical straits, she manages to make the ordeal all about her.

How will this case - which also happens to be Richard's 10,000th surgery - tie into the trials and tribulations of the doctors of Seattle Grace? We'll find out Thursday night in "Hope For the Hopeless."

Check out the sneak preview clip below ...

Steve Marsi is the Managing Editor of TV Fanatic. Follow him on Google+ or email him here.

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Grey's Anatomy Season 8 Episode 12 Quotes

Julia: Love you.
Mark: See ya.

There's nothing else we can do for you. These are the last words a surgeon wants to tell a patient. Getting up doesn't come easy to us, so we do everything in our power not to. For surgeons, lost cause just means try a little harder.