Marcia Wallace, a comedic actress best known to current TV fans as the voice of Edna Krabappel on The Simpsons, passed away last night at the age of 70.

Wallace’s close friend Cathryn Michon - who directed the star's final film - confirmed the news via statement:

“She passed at 9 PM last night due to complications from breast cancer of which she was a long and proud survivor and advocate for women and healing. Ironically it was during breast cancer awareness month during which she was always a funny ray of hope for so many. I’m devastated.”

Wallace won an Emmy for the role of Krabappel and also starred years ago as Carol Kester on The Bob Newhart Show.

“Cheers to the hilarious, kind, fab Marcia Wallace, who has taken her leave from us," The Simpsosns co-star Yeardley Smith blogged this morning. “Heaven is now a much funnier place because of you.”

Wallace also appeared on the panel of many famous game shows, such as Hollywood Squares, The $25,000 Pyramid, To Tell the Truth, Match Game and Family Feud. We send our thoughts and prayers to her family.

UPDATE: Says producer Al Jean in a statement: "I was tremendously saddened to learn this morning of the passing of the brilliant and gracious Marcia Wallace. She was beloved by all at 'The Simpsons' and we intend to retire her irreplaceable character."

UPDATE: Insiders now say Wallace passed away from pneumonia complications.

Matt Richenthal is the Editor in Chief of TV Fanatic. Follow him on Twitter and on Google+.