We're sorry for doing this to you, Grey's Anatomy Fanatics.
But it's time to break out the tissues.
With Sandra Oh set to say goodbye for good on Grey's Anatomy Season 10 Episode 24, television will lose one of its most beloved friendships.
What will Cristina do without Meredith and vice versa? How do you bid farewell to your one special "person?" We don't know. We can't predict the future.
But we can relive the past, thanks to this special ABC tribute video. Watch now and take a look back at the best moments in the Cristina-Meredith friendship:
And, while we're at it, here are a handful of Cristina Yang photos that remind us why we'll miss this expert surgeon: