Grey's Anatomy Sneak Peek: The Charmed Ones Reunite!

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It's finally happening!

Grey's Anatomy Season 16 Episode 3 is staging a Charmed reunion. 

In tonight's episode, Holly Marie Combs and Alyssa Milano will appear as sisters. 

Holly Marie Combs and Alyssa Milano Guest Star - Grey's Anatomy

They played sisters on the OG iteration of Charmed, so this is kind of a big deal. 

ABC has dropped an official sneak off of the actress' first scene together, and it brings back ALL the feels. 

During that pivotal scene, the sisters wonder whether their other sister fell at or in a construction site. 

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Before we get much intel, Richard Weber arrives on the scene to dish the goodies. 

This also confirms the storyline is not taking place at Grey Sloan Memorial, you know since Weber got fired from that hospital. 

Instead, the storyline will take place at Pac North, aka the new hospital both Weber and Karev are working at. 

This special episode, titled "Reunited," is airing as part of ABC's Cast From the Past, a special week of episodes reunites casts of former TV shows. 

It's certainly a different way to market things, but the Charmed reunion, in particular, should be a hit. 

The original Charmed was a popular series that is still talked about to this day. Many fans are still clamoring for a sequel series featuring the original cast, but given that CW has pressed on with a reboot, that will probably never happen. 

"With new restrictions, Meredith tiptoes the line of protocol as she helps Jo with a difficult procedure from afar; and Koracick makes things challenging for Owen at Grey Sloan," reads the official logline for the episode. 

Related: Grey's Anatomy Renewed for Two Seasons

"Meanwhile, a patient at the hospital is brain-dead after falling into a construction site, and her two sisters must decide whether or not to keep her alive, on Grey’s Anatomy."

Watch the full video below. 

Have you missed an episode? Remember, you can watch Grey's Anatomy online right here via TV Fanatic.

Paul Dailly was an Associate Editor for TV Fanatic.Follow him on X.

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Grey's Anatomy Season 16 Episode 3 Quotes

Maggie: He just walked out of the fog with a new girlfriend, like I never existed. I think I might actually hate him.
Zola: My teacher said hating someone is like drinking poison and expecting the other person to die. 
Maggie: Go get ready for school.

Maggie: Does Meredith know?
Amelia: No.
Maggie: Owen?
Amelia: No, no. No one knows.
Maggie: Except for me, who somehow knows about everyone's wombs.