Agnes Skinner is Principal Seymor Skinner's very controlling elderly mother.  Agnes was actually revealed to have adopted Seymour during "The Principal and the Pauper."  Agnes also often serves as a friend of Marge in many adventures.

Agnes Skinner Quotes

I was in love with a soldier boy on leave from Korea. It was a fifties style of romance, five minutes of sex and a lifetime of regret. He went back to his war and I went back to my dream of pole vaulting in the Helsinki Olympics. But there was a bump in the road, a bump named Seymore.

Agnes [in flashback]

Agnes: Where did you learn to sweep like that?
Marge: I've been training all my life. I once swept red wine off a white carpet.

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The Simpsons Quotes

Larry: What you got riding on this?
Homer: My daughter.
Larry: What a gambler!

Maggie? Oh, you must be sick. Let's see, what's old Dr. Washburn prescibe? Do you have dropsy? The grippe? Scofula? The vapors? Jungle rot? Dandy fever? Poor man's gout? Housemaid's knee? Climatic poopow? The staggers? Dum-dum fever?

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