Karen Roe is a character on One Tree Hill, played by Moira Kelly. Karen is Lucas Scott's mother by her ex-boyfriend and high school sweetheart Dan Scott.
Karen Rose also has a young daughter. Her name is Lily Roe Scott and she was conceived with Keith Scott, Dan's brother.
Lucas: A guy drugged Peyton's drink at a party. Brooke called me for help. I took her home, waited until she felt better. Truth.
Karen: As excuses go, that's pretty solid. Is she okay?
Lucas: Did you change your hair?
Karen: If by "change," you mean "drag a brush through it," then yeah.