Sheldon and Amy do a scientific evaluation when she gets turned on by Zach. They determine that she's horny. He wants her to go out with Zach, but instead she tries a hand-holding experiment with Sheldon.
Sheldon: I'll have a diet Coke. Penny: Can you please order a cocktail? I need to practice mixing drinks. Sheldon: Fine... I'll have a virgin Cuba Libre. Penny: That's... rum and Coke without the rum. Sheldon: Yes, and would you make it diet?