Quagmire and Lois in Bed
Quagmire manages to get Lois into his bed when Peter ends up with amnesia and adopts a bachelor lifestyle.

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Show:
Family Guy
Episode:
Family Guy Season 8 Episode 10: "Big Man on Hippocampus"
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Family Guy Season 8 Episode 10 Quotes

Brian: Having sex with Quagmire is inevitable, like a fat guy ordering dessert when everyone else wants to leave.
Waiter: Would anyone like dessert?
Man: I couldn't eat another thing.
Woman: I gotta get home for the sitter.
Fat Man: I'll have the souffle.
Waiter: That takes 45 minutes.
Fat Man: That's okay.

Man: And we're picking you because you have three sons.
Meg: But I'm...
Peter: Shut up, Meg.