Sheldon: How can you sleep? I'm not done making you feel better. I still have to put a cold rag on your head, sing to you, and apply Vaporub to your chest.
Amy: You want you rub something on my chest.
Sheldon: Yes, all over it.
Amy: Maybe we should start with that.
Sheldon: Now you're being a responsible patient.
Sheldon: Now, you may notice some tingling.
Amy: Oh, I'm counting on it.

Amy: Have you considered massage?
Sheldon: I'd like to respond to that sarcastically: Yes, I relish the thought of a stranger covering my body with oil and rubbing it.
Amy: I was proposing you massage your muscles with your OWN hands.
Sheldon: (aback) Still sounds like a lot of unnecessary touching...

Amy: Oh ... are we nervous, Dr. Cooper?
Sheldon: No. What you see is a man trembling with confidence.

... cuz we out dropping science, son.

Amy: Goodnight, Painting Penny. Goodnight, Real Penny.
Penny: Goodnight, Real Amy.
Amy: You don't have to say goodnight to Painting Amy, because she's never leaving. Bernadette: Goodnight, Real Penny. Goodnight, Transvestite Penny.

Amy: The meme has reached full penetration.
Sheldon: Pun intended?
Amy: No. Happy accident.

Not to mention, your acting career is going south like Sherman. Read about it in your book.

I'm just saying, second base is right there.

Amy: Sheldon, I am not going through menopause.
Sheldon: Are you sure? You said that with the testy bark of an old bitty.

Amy: Sheldon, there's something else I've been wanting to say, but before I do, I just... I want you to know that you don't have to say it back.I know you're not ready, and I don't want you to say it just because social convention dictates...
Sheldon: I love you, too.
Amy: You said it.
Sheldon: There's no denying I have feelings for you that can't be explained in any other way. I briefly considered that I had a brain parasite. But that seems even more far-fetched. The only conclusion was love.

Amy: Should I go? I've been told, sometimes, I overstay my welcome.
Leonard: Wha ... who told you that?
Amy: Well, most recently my gynecologist.

Until you manage to upload your intelligence into a self-sustaining, orbiting satellite equipped with high-speed internet and a cloaking device, you will be dependent on the human race.

TBBT Quotes

Oh, Bernadette, please play my clarinet.

Raj's poem

Sheldon: I'll have a diet Coke.
Penny: Can you please order a cocktail? I need to practice mixing drinks.
Sheldon: Fine... I'll have a virgin Cuba Libre.
Penny: That's... rum and Coke without the rum.
Sheldon: Yes, and would you make it diet?