Sheldon: I have some odd freckles on my buttocks. Can I make an appointment for you to look at them?
Emily: Um... okay, I guess.
Amy: I'm with him three years, nothing. She's with two minutes, and he's taking his pants off.

It's a good thing I'm not wearing flag underwear right now because there's about to be a fire.

Sheldon: Did you enjoy my lecture?
Amy: No, and neither did our waiter.

I'm saying, in the spirit of science, what is that little skank's problem?

Amy: I'm stimulating the pleasures of this starfish. I just need to turn it off.
Penny: What happens if you don't?
Amy: Then I have to sit through lunch knowing this starfish is having a better day than I am.

Sheldon: I recently read that during World War Two, Joseph Stalin had a research program to create supersoldiers by having women impregnated by gorillas.
Howard: What a sick use of science.
Raj: Hey, as long as the baby's healthy.
Amy: I wonder if Stalin considered any other animals.
Leonard: Hippos are the deadliest creature. A half-human, half-hippo soldier would be pretty badass.
Howard: Yes, but when they're hungry-hungry, you can stop them with marbles.
Sheldon: Yeah, the correct animal for interspecies supersolider is koala. You would wind up with an army so cute it couldn't be attacked.

How could you let him go?!

Amy: Maybe you'll love living alone.
Sheldon: I don't know. Perhaps.
Amy: And if it turns out you don't ... you and I could live together.
Sheldon: You and... Oh, sure. And while we're at it, why don't we get engaged, too? Why don't we get a little house, start a family? Enjoy our sunset years together? Do you hear yourself, woman?!
Amy: Sheldon, it was just a thought.
Sheldon: No. Here's a thought. You're not moving in, Leonard's not moving out, everything stays exactly the way it is.

Bernadette: Girl Sprouts?
Amy: My mom made it up as an alternative to the Girl Scouts. She didn't want me selling cookies on a street corner like a whore.

Bernadette: This is pretty cool. You don't see too many spherical cakes.
Amy: I wonder why that is.

Sheldon: Amy, mourning the inevitable is a complete waste of time.
Amy: And watching a bunch of goody space movies you've seen hundreds of times isn't?
Sheldon: If we were in a physical relationship, you just lost sex tonight.

Penny: I gave him a new look. It's cute, huh?
Amy: Yeah, it's cute. That's the problem. I don't need other girls to see him walking around like sex on a stick.
Sheldon: She's right. I'm too hot.

TBBT Quotes

Oh, Bernadette, please play my clarinet.

Raj's poem

Sheldon: I'll have a diet Coke.
Penny: Can you please order a cocktail? I need to practice mixing drinks.
Sheldon: Fine... I'll have a virgin Cuba Libre.
Penny: That's... rum and Coke without the rum.
Sheldon: Yes, and would you make it diet?