Brian: Can you believe that cashier's accent? "Would you like some change for you?"
Stewie: If it weren't for 9/11, they'd be adorable!

Brian: Alright so we roll the dice and then we both have to yell Yahtzee really loud.
Stewie: At the same time?
Brian: Yeah and you have to flap your wrists like this. (Flapping his hands in the air.)
Stewie: And you'll do it to?
Brian: Of course, that's how it's done.
Stewie: Okay.
Brian: Alright, ready?
Stewie: Okay, you going to do it with me?
Brian: Oh yeah.
Stewie: (After Brian throws the dice, screams and flaps his hands.) Yahtzee!
Brian: Gay.
Stewie: You suck!

Brian: (After being shocked by Peter.) Damn it Peter, stop it! I got to tell you, you're pissing me off worse when I watched the OJ verdict with my old roommate. (Cuts to scene where Brian and his roommate are watching TV.)
TV Announcer: We, the jury, find the defendant, Orenthal James Simpson, not guilty. (Roommate says "Yes!" while Brian says "What the hell?" simultaneously. There is a moment of silence.)
Brian and Roommate: (simultaneously) What? (They both take out guns and aim at each other.)
Brian: Maybe we should get new roommates.
Roommate: Yeah, maybe we should.

Peter: (After shocking Chris.) What the hell was that? (Shocks Chris again.) Oh my God, Lois, don't get alarmed, but, I think I might be Jesus. I'm Jesus.
Brian: Peter, that's a static shock. Your pajamas created a charge of electricity when you dragged your feet across the carpet and when you touched Chris, you passed it on.
Peter: Kneel before Christ! (Gets up, rubs feet on carpet, shocks Brian.)

Peter: Hello flabby, out of shape family. Check out my bulging ripplyness.
Brian: Peter, you've been to the gym once... for fifteen minutes.
Peter: And I'm fifteen minutes stronger Brian. I'd rip a phone book in half, but for the life of me, I don't know anyone who uses a phone book anymore. So I'll use Meg's laptop.
(proceeds to completely destroy Meg's laptop)

(Brian is sitting on the toilet)
Lois: Well, look at you using the toilet. I am so proud of you.
Brian: Hey, well you deserve all the praise for encouraging me to do it.
Lois: Well still, good for you.
(Lois leaves, and Stewie enters)
Stewie: So, where are you really doin' your business?
Brian: Oh, I found a place.
(Scene cuts to Adam West's mansion, he walks near some bushes
Adam West: Well I'll be damned, and they called me crazy; "You can't plant sausage seeds" they said, well look at this!

(Brian and Stewie are in the bathroom, staring at the toilet)
Brian: How do you think it works?
Stewie: I have no idea.
Brian: Look, Lois told me I had to start using the toilet, and you're the one who's had potty-training, so I'm counting on you to help me.
Stewie: Alright, we're two intelligent guys, we can figure this out.
(they walk toward the toilet)
Brian: What's that big back part?
Stewie: (nervously) Maybe that's where the wizard lives who operates this thing. It would be wise not to anger him.
Brian: (reaching for the flush handle) I wonder what this thing is for.
Stewie: Brian! Be careful with that, we don't know what it does.
Brian: (sighs) Alright, here goes.
Stewie: Oh god, oh god, careful, careful, careful, careful!
(Brian flushes the toilet, they both run out of the bathroom, Stewie yelling and Brian barking)

Lois: (Enters through front door.) Brian, what is this on my shoe?
Brian: My poop.
Lois: (Takes tissue and wipes shoe.) That's right and it's disgusting. I am sick of you using the front yard as your bathroom. It's time you learn to use the toilet like everyone else.
Stewie: Uh, I'm going to sneeze. I'm going to sneeze. I'm going to sneeze. I'm going to sneeze. (Sneezes on tissue with Brian's poop and looks at it.) Ahhhhh! (Runs away.)

Bill Clinton: All right, are you ready for another round of N.A.F.T.A
Lois Griffin: What does N.A.F.T.A. mean?
Bill Clinton: 'Nother Afternoon of F****** That Ass!

Lois: Glen, we're so thrilled for you.
Brian: Yeah. Guess it didn't take much for you to get your job back, now that you're a hero.
Peter: And I'm so happy, I don't mind that I was raped in a federal prison after being arrested for hijacking!

(Peter spits tobacco on the floor)
Brian: Peter, that's disgusting. Here, spit in this cup instead.
(Peter spits in cup and puts it on the arm of the couch)
Stewie: Oh, there's my apple juice.
Brian: Stewie, wait don't-
(Flashback to Stewie beating Brian)
Stewie: Where's my money? You gonna give me my money?
(Flashback ends)
Brian: Oh, nevermind.
(Stewie drinks from the cup and starts yelling)

Brian: You're talking out of your ass!
Stewie: It doesn't matter Brian, I'm tan! Hey, Brian, Brian, Brian... Look at my tan walk!

Family Guy Quotes

Aunt Margarite [on her video will]: Lois, you were always my favorite niece; I just knew you would find a wonderful man who would make all your dreams come true. But I was wrong.
Peter: And now you're dead. Score one for Peter

But now that you mention it, your face looks like a used condom.

Quagmire