Look at these male model sons of bitches. Nice "Blue Steel," Sam.

Misha? Jensen? What's up with the names around here?

Sam: We landed in some dimension where you're called Jensen Ackles and I'm something called a Jared Padalecki.
Dean: So, what? Now you're Polish?

Dude, they put freakin make up on us. Those bastards.

I'm not wearing any makeup. Oh crap. I'm a painted whore.

Hey, you leave my baby alone! She's got nothing to do with this!

Dean: Hey, maybe we'll have a Snooki sighting.
Sam: What's a Snooki?
Dean: That's a good question.

We've been Parent Trapped.

I don't like the way Kim Cattrall is looking at me.

So, what? We've got a bunch of killer dolls? Like Chucky?

Sam: Wait. That anatomy dummy you were molesting at the lab.
Dean: Excuse me?
Sam: What if that's what this is about?
Dean: What exactly are you accusing me of?

Dean: Be my valentine?
Sam: Dude, we're working. Put it back.
Dean: Have a heart.

Supernatural Quotes

Why do they call this place The Empty? It's full. It's full of sorrow and despair playing over and over again of angels and demons dreaming about their regrets. Forever.

Ruby

Weird, creepy, off-the-grid "Children of the Corn" people? Yeah, I’m in.

Dean