I will be Derek Shepherd, the former neurosurgeon who is now a research librarian.

Meredith, I'm alive. We survived. Zola has us both for parents. That's enough.

Always had to be the first.

Derek to Mark

Cristina: What's the t-shirt for?
Derek: I'm going to scream alot, probably pass out.

Mark can buy it. His dreams have always been my dreams.

How's Julia? You impregnate her yet?

Derek: You are making this decision with Cristina.
Meredith: She's not the only factor.
Derek: You should be making this decision with me, your husband.

Meredith: We're staying.
Derek: We're going.

When did I become the advice columnist?

He's happy with the eyeball doctor. So make sure you want him because you want him and not because he's with someone else.

Derek: Come back to me.
Meredith: What's to miss in Neuro?
Derek: Me.

You are so sexy when you are looking at a teratoma.

Grey's Anatomy Quotes

Arizona: Oh my God! I mean, I understand why you're into her. She's hot. Wait, she likes you?
Nathan: What? I mean, I'm going to try not to be offended at that.
Arizona: No, no, no. It's just that Derek was--Derek was epic for her. They were the great love story. I mean, that girl's heart beat for Derek Shepherd. It just...it never occurred to me that she would ever be with anyone else. He was perfect. He was everything. That man turned her world. It...I spooked you. Don't be spooked.

MEREDITH: "You don't get to call me a whore. When I met you, I thought I had found the person that I was going to spend the rest of my life with. I was done! All the boys and all the bars and all the obvious daddy issues, who cares? I was done. You left me. You chose Addison. I'm all glued back together now. I make no apologies for how I chose to repair what you broke. You don't get to call me a whore."
DEREK: "This thing with us is finished. It's over."
MEREDITH: "Finally."
DEREK: "Yeah, it's done."
MEREDITH: "It is done."