Howard: No ... about my job. I want you to tell me I'm good at what I do.
Sheldon: You're obviously good at what you do.
Howard: Well, then why are you always ripping on me?
Sheldon: Oh, I understand the confusion. I have never said that you are not good at what you do, it's just that what you do is not worth doing.

Howard: Well, we appear to have reached an impasse. And, you know, I have to say, I thought you'd be more upset that your laptop is sitting on my junk.
Raj: I didn't pick up on that. That's a nice touch.

Raj: Ahh, the premature I love you.
Wolowitz: : I guessed premature, does that count?

Wolowitz: Okay, what if I were to tell you, tomorrow at 4:30, you could meet a woman who has been scientifically chosen to be your perfect mate?
Sheldon: I would snort with derision and throw my arms in the air, exhausted by your constant tomfoolery.

Sheldon: Is anyone else troubled by the Spider-Man theme song?
Leonard: Why would it trouble you? It's like your third favorite cartoon theme song.
Sheldon: It is, right behind [Sheldon sings "Inspector Gadget" and "Teenage Mutant Ninja Turtles" theme songs]
Sheldon: However, the Spider-Man lyrics posit that Spider-Man's Spider-Man does whatever a spider can.
Howard: Yeah, so?
Sheldon: I can think of many things that Spider-Man can't do that a spider can. One crawl in your ear and die, two legally leave Guatemala without a passport, and three have sex with a spider.

Howard: What do you want us to do about it?
Sheldon: You clearly weren't listening to my topic sentence: Get your women in line!

Wolowitz [about Sheldon]: How long's he been stuck?
Leonard: Intellectually about 30 hours, emotionally about 29 years.
Wolowitz: Have you tried rebooting him?
Leonard: No, I think it's a firmware problem.

Leonard: I'm her friend, I'm not going to take advantage of her vulnerability.
Wolowitz: Wait, so you're saying that if in the depths of despair she throws herself at you and demands you take her right there, right now, you'll just walk away?
Leonard: I said I'm her friend, not her gay friend

Raj: Okay, I'm going to play it cool. Tell her, "Maybe. Whatever, babe."
Howard [translating in sign language to Emily]: He'll text you.

Howard: You know, there's a saying we have at NASA. What makes the right stuff so right is that it always comes home.
Bernadette: Stop talking, Howard.

Wolowitz: I once dated a girl who believed she was abducted by aliens.
Leonard: And that didn't bother you?
Wolowitz: Au contraire; it meant she was gullible and open to a little probing.

Wolowitz: This is the thing from the pizza box that keeps the lid from touching the cheese.
Raj: Is that what this is for? In India, the lid just touches the cheese. Of course, we also have rampant poverty and periodic outbreaks of chlorea so a little cardboard on our cheese is no biggie

TBBT Quotes

Oh, Bernadette, please play my clarinet.

Raj's poem

Sheldon: I'll have a diet Coke.
Penny: Can you please order a cocktail? I need to practice mixing drinks.
Sheldon: Fine... I'll have a virgin Cuba Libre.
Penny: That's... rum and Coke without the rum.
Sheldon: Yes, and would you make it diet?