Izzie: You want lessons, huh?
Alex: I want lessons.
Izzie: Okay. You start with 'Isobel Stevens, you are staggeringly good in bed. You are amazingly smart, wonderfully funny, and you care about animals.'
Alex: That's where I start?
Izzie: Mmm. And then you say 'Do you wanna go steady with me?'
Alex: That's what I would say if it was 1952.
Izzie: Alex? Do you wanna go steady with me.
Alex: If that's what you want, I mean yeah, whatever.

Izzie: Thought you were sleeping with Michelle tonight. Or was it Jackie?
Alex: Izz ...
Izzie: I've had a hard day Alex. Would you please just leave me alone?
Alex: Izzie ...
Izzie: What!
Alex: I'm not good at this. I'm not good at ... relationships or talking about stupid feelings. And you are, so maybe you could teach me or something. Tell me where I go wrong.
Izzie: [pauses] You don't want us to see other people. You don't want us to see other people and that's how you tried to tell me! [laughs] By asking if it was cool if you screw Michelle.

Alex: What's wrong with you?
Izzie: What's wrong with me? We've been sleeping together for a week and already you're bored. I am hot! And great in bed. So what is wrong with YOU?

Alex: I didn't say I was bored. I just asked whether I should keep sleeping with Michelle. I'm asking if you're all in! What's so wrong with that.
Izzie: You're a barbarian. How can I be all-in with an actual barbarian?
Alex: Fine. Holly in radiology thinks I have a hot ass. I'll tap that next.
Izzie. You do that.

You can't blame yourself. Some people are just broken. I guess you just try not to care too much and you can't be disappointed.


Richard: What are you people doing?
Izzie: We were just, uh, just deciding which of our interns to give to George.
Cristina: Uh huh.
Miranda: Oh, you think I got to choose my interns? And I picked you people... 'cause you're all such a surgical dream team? [to Alex] You, you're lazy. [to Izzie] You're whiney. [to Meredith] Butter fingers over there... downright depressing. [to Cristina] You, Yang, you're just annoying. Choosing their own interns! What are ...
Richard: Give me those damn cards. [picks out four, hands cards to George] O'Malley, you have interns.

Izzie: Graciella charts like crap. But she can put in a line. Claire, on the other hand, nearly castrated a guy with a catheter.
Lexie: We can hear you!
Alex: I might dump Pearson.
Izie: Oh, why does he suck?
Alex: I just hate saying the name Pearson.
Izzie: Hmm.

Meredith: Excuse me! What is going on?
Izzie: Trying to decide which of our interns to give to George.
Lexie: In front of us, they're deciding in front of us. Like livestock at a state fair.
Cristina: I think I'll keep Lexipedia. She remembers many things... and she bathes, which is much more than i can say for stinky 2 over there. You smell.

Izzie: And I know you care about me too and it's not too late for us.
Alex: Get outta my room.
Izzie: Admit it. I know you care about me too I know you do. I care about you. I care about you. I care about you. I care about you. I care about you! I- [they kiss]

Izzie: I care about you, and I'm not gonna go crazy, and I'm not gonna try to kill myself and I'm not gonna stop caring about you no matter how hard you push me away.
Alex: Shut up and get outta my room.

Izzie: Maybe he just cares about his son but the moron is too emotionally stunted to let him.
Alex: See, this, this right here is your problem. You get all wrapped up and involved and you start caring about these people! Your patient in there? He's the moron. His son's never gonna give him what he wants and he's just gonna be disappointed! And the sooner he gets that the sooner you get it, and ...
Izzie: No, go on please. Be a selfish ass. Because then at least I know what to expect. This whole 'be a nice guy one minute and a total jerk the next' is getting really. Old. Alex. So who's it gonna be? Pick. One.

Meredith: I don't even want the credit, but the clinical trial was my idea. And I had to beg him to do it. More than once.
Izzie: It's okay if you want the credit. I would want the credit.
Cristina: When you screw the attendings you get screwed. They have all the power.
Lexie: Interns, you could screw interns. Date, you could DATE interns. Because we're so non-threatening.

Grey's Anatomy Quotes

Arizona: Oh my God! I mean, I understand why you're into her. She's hot. Wait, she likes you?
Nathan: What? I mean, I'm going to try not to be offended at that.
Arizona: No, no, no. It's just that Derek was--Derek was epic for her. They were the great love story. I mean, that girl's heart beat for Derek Shepherd. It just...it never occurred to me that she would ever be with anyone else. He was perfect. He was everything. That man turned her world. It...I spooked you. Don't be spooked.

MEREDITH: "You don't get to call me a whore. When I met you, I thought I had found the person that I was going to spend the rest of my life with. I was done! All the boys and all the bars and all the obvious daddy issues, who cares? I was done. You left me. You chose Addison. I'm all glued back together now. I make no apologies for how I chose to repair what you broke. You don't get to call me a whore."
DEREK: "This thing with us is finished. It's over."
MEREDITH: "Finally."
DEREK: "Yeah, it's done."
MEREDITH: "It is done."