This might come as a shock, but looks like I'm the respectable adult in this situation.

Sorry about that. Your breasts are fantastic. I wouldn't change a thing.

Teddy: I wanted to talk to you about breast implants.
Mark: Good for you! It crossed my mind the first time I saw you, but I didn't think you'd go for it.

I wanna build a life and a family. And I'm not wasting my time on someone that doesn't share that interest.

Callie: Find a grownup that you like and date, like a grownup.
Mark: I don't know what that means.

Derek: Screwing drugs reps isn't gonna make you feel better.
Mark: Yeah, it is.

That's the Sloan nose. Can you see it? That's my dad's nose! He's got the Sloan nose ...

Mark: Torres, you know anything about putting together cribs?
Callie: You got a crib?
Mark: Sloan's coming home this week and I got one and I put it together but it wobbles. It can't wobble!
Callie: You're like a sweet dad now. I hardly recognize you.
Mark: Who's that new blonde over there? I may be a dad, but I'm still a single dad. Excuse me.

Mark: Ahhh! What did you do to your hair?
Lexie: I changed it! [pauses] You thought I was someone else. And you were hitting on me! You are pathetic, and hypocritical and slutty.

[to Lexie] You can't pull it off! Blondes are either bad ass or fun. You're ... you're a brunette!

I'm not the one whose immature. And you made me wreck my skin graft.

Mark: I made a bet she wouldn't make it down that aisle. Won $50.
Owen: What aisle?
Mark: You never heard that story? That's a good story.

Grey's Anatomy Quotes

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)

Arizona: Oh my God! I mean, I understand why you're into her. She's hot. Wait, she likes you?
Nathan: What? I mean, I'm going to try not to be offended at that.
Arizona: No, no, no. It's just that Derek was--Derek was epic for her. They were the great love story. I mean, that girl's heart beat for Derek Shepherd. It just...it never occurred to me that she would ever be with anyone else. He was perfect. He was everything. That man turned her world. It...I spooked you. Don't be spooked.