Agent Ward and I been having sex.

Coulson: Alright what’s up?
May: You tell me?
Coulson: You’re talking, more than ever.

Ward: You let her get tossed.
May: All I did was tell Hand the truth. Skye is no use to us on this plane.
Ward: How can you say that?
May: She’s not. Not with all these agents here, over her shoulder monitoring her every move.
Ward: You wanted her off the plane.
May: Outside the system, that’s how Skye works best. You don’t have to assume the worst in me.

Melinda: You taking a punch for me. I don’t need your protection.
Ward: You think I don’t know that. I took that punch because you’re faster than me. You can do more good on your feet. It was tactical not personal.
Melinda: My mistake.
Ward: I’m not some recruit who can’t separate church from state. I’m on the same page as you. So don’t flatter yourself.

Coulson: What did you say to her?
Melinda: The same words you said to me in Bahrain.

You can't undo what's been done, that will be with you forever. But trying hold to this life, clinging to the person you thought could be, that's hell.

Coulson: I can’t think of a single time when anything alien in human hands ended well.
Skye: Wouldn't mind getting my human hands on Thor. He’s so dreamy.
Coulson: Sure he’s handsome but
May: No he’s dreamy.

You died. There's no way you can go through a trauma like that and not come out of it changed.

Melinda: You can't save someone from themselves, sir.
Coulson: You can if you get to them early enough [looks at Skye].

May: What is your gut telling you now.
Coulson: That she's still hiding something.

Coulson: Go ahead, say it.
May: I don't do petty.
Coulson: But you called it. I trusted my gut even though you said she was a risk.
May: When someone breaks into my house, I usually don't invite them to stay. But that's me.
Coulson: That's me too. Then that alien staff when through my heart.
May: Sure it didn't go through the brain?
Coulson: You really don't do comforting either do you?

May: Bus to short bus.
Ward: Go for short bus.
Coulson: Next time I'll decide what we call ourselves, ok.

Agents of S.H.I.E.L.D. Quotes

Kasius: Yo-Yo Rodriguez? How peculiar.
Yo-Yo: Says the space mime!

Sousa: Hey, what are you doing up?
Daisy: Why do you care?
Sousa: Because you don't.