MEREDITH: "Lets play the game of whose life sucks the most. I'll win. I always win."
CRISTINA: "You don't want to play with me."
Meredith: "Oh yes, I do. I'll even go first. Derek is married, as in pig-headed adulterous liar married." [George spits out his beer]
CRISTINA: "George, you have beer... coming out of your nostrils..."
MEREDITH: "Alright, your turn."
CRISTINA: "I'm pregnant. There. I win." [Joe the Bartender collapses] "Okay, maybe Joe wins."

CRISTINA: "What've you got?"
MEREDITH: "Bomb in a body cavity."
CRISTINA: [shakes head] "Man! All I have is Bailey's husband's open brain."

MEREDITH: "How do you know I did something and not George?"
ALEX: "Because. Bambi looks upset and you look guilty."

[narrating] "There's an old proverb that says you can't choose your family. You take what fate handa you. And like them or not, love them or not, understand them or not, you cope. Then there's the school of thought that says the family you're born into is simply a starting point. They feed you, clothe you, and take care of you until you're ready to go out into the world. There you find your own tribe."

MEREDITH: "We know he cheated on you. That's why we let you turn the house into Santa's Freaking Village. We're not big on holidays. We're trying to be supportive, because you're having a hard time. But right now, Alex is having a harder time."
IZZIE: "Why should anybody care what kind of time Alex is having!?"
MEREDITH: "Because he's Dirty Uncle Sal!"
IZZIE: [looks confused]
MEREDITH: "Dirty Uncle Sal. The one who embarrasses everyone at holidays and family reunions and who can't be left alone with the teenage girls, but you have to invite him anyway. Look... I have a mother who doesn't recognize me and as far as family goes, you guys are it. So I know you're pissed at Alex, but maybe... maybe you could try and help him anyway. Like, in the spirit of this holiday you keep shoving down everybody's throats."

GEORGE: [looking at Dr. Bailey] "Look at her! She's almost as wide as she is tall."
MEREDITH: "Are her ankles swollen?"
IZZIE: "It's gonna be weird when she goes on leave."
CRISTINA: "Leave? She's going on leave?"
MEREDITH: "That's usually what happens when people push babies out of their vaginas."
GEORGE: "You think we'll get a new resident?"
ALEX: "Nah. They'll probably just leave us all unattended, see how much damage we can do."
IZZIE: "Yeah, well, you would know."

GEORGE: "It looks like Santa threw up in here."
MEREDITH: "Just go with it, we're being supportive here."
IZZIE: "Did I go overboard? I know sometimes I can go too overboard."
MEREDITH & GEORGE: [together] "It's great."
IZZIE: "Oh, good. Yay! I love Christmas!"
MEREDITH & GEORGE: [together] "We know."

[narrating] "It's an urban myth that suicide rates spike at the holidays. Turns out they actually go down. Experts think it's because people are less inclined to off themselves when surrounded by friends and family. Ironically, that same family togetherness is thought to be the reason that depression rates actually do spike at the holidays... Okay. Izzie doesn't count."

[narrating] "Who gets to determine when the old ends and the new begins? It’s not on the calendar, it’s not a birthday, it’s not a new year. It’s an event, big or small, something that changes us. Ideally, that gives us hope, a new way of living and looking at the world, a way of letting go of old habits, old memories. What's important is that we never stop believing we can have a new beginning, but it's also important to remember that, amid all the crap, there are a few things worth holding on to."

MEREDITH: "Free time sucks."
GEORGE: "When would have been a good time to hear about your boyfriend's wife?"
MEREDITH: "Are you mad at me or something?"

Meredith: Hi.
DEREK: [walks into elevator] "Hi. Leaving?"
MEREDITH: "80-hour limit. You?"
DEREK: "Surgery was postponed." [smiles]
MEREDITH: [pauses] "I have a dog."
DEREK: "You have a dog."
MEREDITH: "My point is, I have a dog."
DEREK: [smiles] "You have a dog. Oh, and you know what? I love dogs."
MEREDITH: "I've moved on, so don't give me that look."
DEREK: "What look?"
MEREDITH: "That look. Our look. I'm over you."
DEREK: "I'm over you, too."
MEREDITH: "You are?"
DEREK: "No."
MEREDITH: "Oh. Well, I am. Over you."
DEREK: "I'm over you too."
MEREDITH: "You just said... shut up." [smiles]

MEREDITH: [petting the dog] "Such a good dog! Who's Mommy's good boy?" [looks at Izzie and George] "C'mon, what are you doing? We're gonna be late."
GEORGE: "Um, we need to talk about the dog."
IZZIE: "That's not a dog, this is a hyena that escaped from the zoo and dressed up in a dog's clothing."
GEORGE: "Whatever. I don't chew up his clothes. I don't urinate on his bed. I don't try to mount him from behind."
IZZIE: "Mount you from behind?"
GEORGE: "He tried to."

Grey's Anatomy Quotes

[walking by Izzie's room]
Meredith: Hot.
Sadie: Horny.

Sexual sorbet? Hahaha! I love it.

Bailey