Sheldon: But you don't have a life-threatening condition. Why would you take the risk of surgery?
Leonard: Sheldon, it's a routine procedure.
Penny: I've heard you complain about his snoring.
Sheldon: We... Yes, for the first five or six years, but I've gotten used to it. It helps me sleep. He's like my mucus-powered white noise machine.

Penny: Here's a question-- as an alien pretending to be human, are you planning to engage in any post-prom mating rituals with Amy?
Sheldon: There are post-prom mating rituals?
Penny: Not always. Unless your date drives a van with an air mattress, then always.
Sheldon: Well, if it's part of the prom experience, then I'm open to it.
Penny: You're kidding.
Sheldon: I may be an alien, but I have urges.If Amy wants to copulate by firing her eggs into space, well, then, I will happily catch them with the reproductive sac on my upper flermin. I'm not the best at reading facial cues, but I can see that you're a little turned on.

Penny: Prom is silly anyways.
Bernadette: Easy for you to say; you probably went with the captain of the football team.
Penny: No. I just made out with him a little while his date was puking.

Penny: That, believe it or not, is my prom dress.
Bernadette: Wow, you still have it? I just assumed it was balled up in the corner of a barn somewhere.
Penny: What kind of teenager did you think I was?
Bernadette: Slutty.
Amy: Easy.
Penny: The word is "popular."

Penny: You locked them in your basement?!
Dr. Lorvis: Well, they're, they're not locked in. The door just sticks.
Penny: Okay, so how do they unstick it?
Dr. Lorvis: They'd need the key.

Penny: The real question is: What is he doing in your apartment?
Leonard: Oh, he was upset. So Sheldon invited him in for a hot beverage.
Penny: You were okay with that?
Leonard: No. I got upset! And Sheldon made me a hot beverage, too.

You know, maybe if fashion magazines had female scientists in them, I would've become a theoretical physicist. Stop smirking at each other.

Okay, what's the big deal? Look, if it helps me make a sale with a physician, I don't think it hurts to flirt a little. I mean, laugh at their joke, touch their arm, maybe crank up the AC in the car beforehand, you know, to wake up the girls.

Amy: Bernadette is a successful microbiologist. She should be celebrated for her achievements, not her looks. I mean, what kind of message does that send?
Penny: I think the message is -- "Check out the rack on that scientist."

Penny: What should I have done? Taken a picture of us in the car
and put it in a pink frame with puffy paint around it that says "best fiance ever"?
Leonard: Doesn't sound that bad.
Penny: Well, good, because... that's why I did!

Penny: Wait, hang on-- you guys are gonna work in a mine?
Sheldon: Why not?
Penny: You had a panic attack when we went through the car wash.

Penny: I hate her.
Emily: I hate her.

TBBT Quotes

It's very simple. Scissors cuts paper, paper covers rock, rock crushes lizard, lizard poisons Spock, Spock smashes scissors, scissors decapitates lizard, lizard eats paper, paper disproves Spock, Spock vaporizes rock, and, as it always has, rock crushes scissors

Sheldon

Sheldon: Why do you have the Chinese character for "soup" tattooed on your right buttock?
Penny: It's not "soup," it's "courage."
Sheldon: No it isn't. But I suppose it does take courage to demonstrate that kind of commitment to soup.
Penny: How'd you see it? You said you wouldn't look.
Sheldon: Sorry. As I told you, the hero always peeks.