CRISTINA: "What the hell is this?"
PRESTON: "It's a key."
CRISTINA: "Why?"
PRESTON: "Why is it a key? Are we feeling existential this morning?"
CRISTINA: "Well, if the key turns in a lock, and no one asked for the key or even wanted the key, does it make a sound?"

• Permalink: What the hell is this? It's a key. Why? Why is it a key? ...
• Added: July 16, 2006

[to Meredith & Cristina] "This is a men's room. Either whip one out, or leave."

• Permalink: This is a men's room. Either whip one out, or leave.
• Added: July 11, 2006

[to Cristina] "You do enjoy crossing the line, don't you?"

• Permalink: You do enjoy crossing the line, don't you?
• Added: July 11, 2006

PRESTON: "I think you should know that Richard promised Chief to both of us... but you already knew that."
DEREK: "Yeah, well, keep your friends close and your enemies closer."
PRESTON: "No. You're not the enemy, you're just the competition."

• Permalink: I think you should know that Richard promised Chief to both of ...
• Added: July 05, 2006

PRESTON: "Anything you say in the next 30 seconds is free, starting right now."
MIRANDA: "I think you’re cocky. Arrogant. Bossy and pushy. You also have a God complex and don’t think of anybody but your damn self."
PRESTON: "But, I-"
MIRANDA: "Wait. I still have 23 seconds and I’m not done."

• Permalink: Anything you say in the next 30 seconds is free, starting right...
• Added: July 05, 2006

PRESTON: "What the... what the hell is this? Does anybody know what this is?"
MEREDITH: "Oh my God."
PRESTON: [holds body part] "What is it, Grey?"
MEREDITH: "She bit it off-"
PRESTON: "What is it? Spit it out, Grey."
MEREDITH: "That's his.. penis."

• Permalink: What the... what the hell is this? Does anybody know what this ...
• Added: July 05, 2006

"The only person that can keep a promise that big is God, and I haven't seen him holding a scalpel lately."

• Permalink: The only person that can keep a promise that big is God, and I ...
• Added: July 05, 2006

PRESTON: "I guess we never really got our date."
CRISTINA: [smiles] "Are you kidding? That was the best date I've ever been on."

• Permalink: I guess we never really got our date. Are you kidding? That ...
• Added: May 30, 2006

PRESTON: "Dr. Yang, you're handling the saw."
CRISTINA: "You won't let me pick the wine, but this you'll let me do?"

• Permalink: Dr. Yang, you're handling the saw. You won't let me pick the ...
• Added: May 30, 2006

WOMAN IN RESTAURANT: "Oh my God! Is there a doctor here?"
CRISTINA & PRESTON: "Yes!"

• Permalink: Oh my God! Is there a doctor here? Yes!
• Added: May 30, 2006

PRESTON: "So... it's date night."
CRISTINA: "Yeah, it's a night... with a date."

• Permalink: So... it's date night. Yeah, it's a night... with a date.
• Added: May 30, 2006

[the cast, narrating]
MEREDITH: "Human beings need a lot of things to feel alive."
GEORGE: "Family"
CRISTINA: "Love"
IZZIE: "Sex"
DEREK: "But we only need one thing"
RICHARD: "To actually be alive."
CRISTINA: "We need a beating heart."
ADDISON: "When our heart is threatened"
ALEX: "We respond in one of two ways."
GEORGE: "We either run or-"
IZZIE: "We attack."
RICHARD: "There's a scientific term for this."
ALEX: "Fight..."
ADDISON: "...or flight."
MIRANDA: "It's instinct."
MEREDITH: "We can't control it."
IZZIE: "Or can we?"

• Permalink: Human beings need a lot of things to feel alive. Family...
• Added: May 16, 2006