Sam: So, strip club?
Dean: What?

Dean: Look, I've been down this road before, and I fought my way back, I will fight my way back again.
Sam: How?
Dean: Same way I always do: bullets, bacon and booze. A lot of booze.

Look, if there's one thing Dean respects, it's effort. So come along, help us out. Let's go be the good guys.

Dean: And what about Cas?
Sam: What about Cas?
Dean: He manipulated him. He made him promises. Paradise on Earth. And Cas bought it. And you know what that got him? It got him dead. Now you might be able to forget about that, but I can't!

Dude, you were hallucinating sheep on the road.

Sam: Wait, wait, wait, wait! Talk to me!
Teen Dean: Really Sam? Now? I got no grass on the infield and a girl's gonna die. Sorry if I'm not in a chatty mood. Look. You wanted me back in the game, I'm back in the damn game. C'mon.

Sam: Were you racing me?
Dean: No, I was kicking your ass.
Sam: Very mature.

Sam: So, now ah, what's the deal with all this TV crap?
Castiel: Pardon me?
Dean: Yeah, amen Padaleski.
Sam: Padalecki.,
Dean: What?
Sam: -Lecki, I'm pretty sure.

Dean: Seriously. Why? Why would anybody want to watch our lives?
Sam: Well, according to the interviewer, not very many people do.

Sam: What am I? Dracula?
Dean: George Hamilton Dracula.

Wow. I must be the star of this thing.

Sam: We landed in some dimension where you're called Jensen Ackles and I'm something called a Jared Padalecki.
Dean: So, what? Now you're Polish?

Supernatural Quotes

Why do they call this place The Empty? It's full. It's full of sorrow and despair playing over and over again of angels and demons dreaming about their regrets. Forever.

Ruby

Weird, creepy, off-the-grid "Children of the Corn" people? Yeah, I’m in.

Dean