[narrating] "Responsibility. It really does suck. Unfortunately, once you get past the age of braces and training bras, responsibility doesn't go away. It can't be avoided. Either someone makes us face it or we suffer the consequences. And still adulthood has it perks. I mean the shoes, the sex, the no parents anywhere telling you what to do. That's, pretty damn good."

MEREDITH

IZZIE: [picks up coffee cup]
GEORGE: "Do you even know who’s that was?"
IZZIE: "I’m hoping it was yours."
GEORGE: "Nope."

IZZIE: [comes home, sees Meredith drunk] "Holy Mother of Destruction."
MEREDITH: "You missed Doctor Palooza."
IZZIE: "Apparently you didn't."
MEREDITH: "I should probably never speak to you again."

DEREK: [in the car] "Sounds like the party's winding down. We should probably sneak inside now."
MEREDITH: "I think we've done enough sneaking for tonight. It was good sneaking, but enough sneaking."
DEREK: "Yeah, I'd say we're pretty good sneakers."
MIRANDA: [knocks on the window] "You mind moving this tail wagon? You are blocking me in."
DEREK: "Apparently not good enough."

DEREK: [arrives at the party] "You know, in some states, you could get arrested for that... So you blew me off for a bottle of tequila? Tequila's no good for you. It doesn't call, doesn't write, not nearly as much fun to wake up to."
MEREDITH: [kisses him] "Take me for a ride, Derek."

HANK: "Is, uh, Izzie Stevens..."
CRISTINA: "You must be Hank... he's very large and hockey-like. No, Izzie's not here right now."
GEORGE: "You and Izzie will give birth to very tall blonde people. Kind of like Barbies."
HANK: "Izzie said she was going to be at home, she didn't say there was gonna be a party."
MEREDITH: "Which pisses both of us off. Would you like some tequila? It helps."
HANK: "When do you think she’s gonna get here?"
MEREDITH: "Don’t know. But we’re low on ice, Hank."
HANK: "I’m serious."
MEREDITH: "So am I. We’re interns, Hank. Hospital owns us. It’s what we do."
HANK: [leaves]
GEORGE: "Bye."
MEREDITH: "Nice to meet you."

MEREDITH: [playing cards] "Why did we want to be surgeons anyway?"
GEORGE: "Surgery is very serious business."
CRISTINA: [burps]
GEORGE: "Full house."
CRISTINA: "Royal flush. Get naked, baby boy!"

MEREDITH: "Where is Izzie?!"
GEORGE: "She didn’t clear it with you?"
MEREDITH: "This was supposed to be a meet-the-boyfriend, get together little thing."
GEORGE: "I... Iz-izzie has a lot of friends."
MEREDITH: "Izzie doesn’t know this many people."
GEORGE: "I told her to clear it with you."
MEREDITH: "I can’t handle this."
GEORGE: "You want me to kick everyone out? I’m gonna kick everyone out."
CRISTINA: [drunk] "Baby! You made it! Woo!"
MEREDITH: [pauses] "Screw it."

"Izzie I'm going to kill you."

MEREDITH

GEORGE: "Is Meredith the only person in the hospital who doesn’t know the size of this thing?"
IZZIE: "I’m telling her."
CRISTINA: "You can’t. She’s gone already."
IZZIE: "What? Already?"
CRISTINA: "I think she had, excuse me, an errand to run."
IZZIE: "You don’t think Meredith’s really going to mind about the party, right?"
GEORGE: "I want you to make it very clear to her that I had nothing to do with this party. Nothing."

GEORGE: "You paged me?"
IZZIE: "I’m gonna be a while. Do you think you could get home to sign for the beer?"
ALEX: "Why don’t you have your boyfriend sign for it?"
IZZIE: "You have a very annoying way of sneaking up on people. Maybe if you were a little less creepy."
ALEX: "I wouldn’t come anyway. I hate big parties."

IZZIE: "Hey, Hank and I have great sex, all the time. In fact we'll probably have sex after the party, or during the party."
GEORGE: "As long as you clear it with Meredith."
IZZIE: "Hank just needs to realize that doctors can have fun. We’re not all workaholics with God complexes."
CRISTINA: "We ARE workaholics with God complexes."

Grey's Anatomy Season 1 Episode 5 Quotes

[narrating] "Remember when you were a kid and your biggest worry was, like, if you'd get a bike for your birthday or if you'd get to eat cookies for breakfast. Being an adult? Totally overrated. I mean seriously, don't be fooled by all the hot shoes and the great sex and the no parents anywhere telling you what to do. Adulthood is responsibility. Responsibility, it really does suck. Really, really sucks. Adults have to be places and do things and earn a living and pay the rent. And if you're training to be a surgeon, holding a human heart in your hands, hello? Talk about responsibility. Kind of makes bikes and cookies look really, really good, doesn't it? The scariest part about responsibility? When you screw up and let it slip right through your fingers."

MEREDITH

"I guess we're adults. The question is, when did that happen, and how do we make it stop?"

MEREDITH