PRESTON: "I've never done a bovine replacement before, I don't know what I'm doing."
CRISTINA: "So look it up, research it and get someone to assist you."
PRESTON: "It’s not that easy."
CRISTINA: "This is a problem that has a solution, Burke. There are a lot of problems that don't."

CRISTINA: "Look, if you think you’re gonna get any, think again. I'm not in the mood."
PRESTON: "I'm not in the mood either."
CRISTINA: "Good. What do you want?"
PRESTON: "Nothing, I just haven't seen you all day."
CRISTINA: "So I'm working."

GEORGE: "How’s a pompous cocky jackass like you always have women all over him?"
ALEX: "Little bluebell pills. Lots of them."
GEORGE: "Oh, c'mon."
ALEX: "Float like a butterfly, sting like a bee. O'Malley, you think too much. Can’t you see it? You gotta dance and jab, dance and jab! Like me. I am the Ali of this place."

"You're into me. I can tell. Dr. Small and Angry was a hot appetizer, but you, doc, are a smorgasbord of lust."


"Well, you were wrong. You don't always get what you expect do you."


CRISTINA: "Dr. Bailey, I want off the psychic case, I'll take whatever you've got. Can I switch?"
MIRANDA: "Ask nicely."
CRISTINA: "What? This is me doing nicely."

MEREDITH: "Where'd you grow up? What's your favorite flavor of ice cream? Where'd you spend your summer vacations?"
DEREK: "Oh, lighten up. It'll be good for your blood pressure."
MEREDITH: "Don't you tell me to lighten up. I'll lighten up when I... feel light."

MEREDITH: "Give me something to go on. Anything! What are your grandparents’ names?"
DEREK: "I don't have grandparents."

MEREDITH: "I want facts, and until I get them, my pants are staying on."
DEREK: "Or you could just roll with it, be flexible. See what happens."
MEREDITH: "I'm not flexible."
DEREK: [laughs] "Now there I disagree... We'll find these things out. That's the fun part, you know? That's the gravy."

"I'm a surgeon, I don't have any friends."


OTHER INTERN: "He thinks his seizures are visions"
PATIENT: "Hello, they’re not seizures, I’m psychic."
CRISTINA: "Yeah, and I’m a chicken."

CRISTINA: "Okay, you know the talking part?"
CRISTINA: "I’m not interested."

Grey's Anatomy Season 1 Quotes

[narrating] "At some point, you have to make a decision. Boundaries don't keep other people out, they fence you in. Life is messy, that's how we're made. So you can waste your life drawing lines or you can live your life crossing them. But there are some lines that are way too dangerous to cross. Here's what I know. If you're willing to throw caution to the wind and take a chance, the view from the other side... is spectacular."


"I need a drink, a man, or a massage. Or a drunken massage by a man."