Last time I saw that look on an editor’s face, I’d just handed in "Bugs."

Chuck

Sam: Let’s pick up a six-pack.
Dean: Just six?

Sleeping is the new smoking.

Dean

He who hesitates, disintegrates.

Lucifer

Apparently archangel plus God power doesn’t trump God’s sister.

Sam

This is exactly how we screw ourselves. We make the heart choice instead of the smart choice.

Sam

I'm going to come back for you. OK? I promise.

Dean

Game’s over, Dean. No more second chances. No more extra lives. Time to say bye bye to Luigi, Mario.

Billie

I told you that roadhouse chili was a bad idea.

Sam

You can't save everyone.

Rufus

I'm worried about my boys.

Bobby

Bobby: Were you ever nice?
Rufus: 1985. Worst year of my life.