Sheldon: Hmmm... what kind of tea is appropriate for winning a Nobel Prize and now everything is changing and you feel unmoored from reality?
Leonard: I dunno. Earl Grey?

Howard: Dinner ready?
Bernadette: Not unless you cooked.

Siebert: Hey fellas, can you do me a favor?
Raj: Do we have a choice?
Siebert: HA HA! No.

Amy: It's weird. I don't really feel different but I guess our lives will never be the same.
Sheldon: I don't know. We're going to work like always. I still put my pants on both legs at a time.
Amy: One day, that's going to end very badly.

Sheldon: You know, when you think about it, now that we're Nobel Prize winners, our names will be linked together forever.
Amy: We're married. Our names are already linked together forever.
Sheldon: Oh please! That's just a piece of paper. This is a piece of paper and a medal.

Sheldon: How's it feel to be married to a Noble Prize winner?
Amy: You tell me.
Sheldon: Oh, Amy-centric! What a fun way to look at it.

You have your whole life to smack him around. This is MY time!

Leonard

Penny: Should we wake him up?
Leonard: Well, he did say if he fell asleep we were allowed to slap him awake.
Penny: Oh boy!

Sheldon: The only drug I need is the endorphins pumping through my brain in anticipation of our victory.
Amy: Well, technically, anticipation wouldn't be mediated by endorphins as much as dopamine but, y'know, you've been up all night so I'll give you that one.

Penny: Leonard? Coffee?
Leonard: Black and strong like Luke Cage.
Penny: I'm too tired to even be disturbed by that.

The Big Bang Theory Season 12 Episode 24 Quotes

Sheldon: The only drug I need is the endorphins pumping through my brain in anticipation of our victory.
Amy: Well, technically, anticipation wouldn't be mediated by endorphins as much as dopamine but, y'know, you've been up all night so I'll give you that one.

Penny: Leonard? Coffee?
Leonard: Black and strong like Luke Cage.
Penny: I'm too tired to even be disturbed by that.