Sheldon: Hmmm... what kind of tea is appropriate for winning a Nobel Prize and now everything is changing and you feel unmoored from reality?
Leonard: I dunno. Earl Grey?

Howard: Dinner ready?
Bernadette: Not unless you cooked.

Siebert: Hey fellas, can you do me a favor?
Raj: Do we have a choice?
Siebert: HA HA! No.

Amy: It's weird. I don't really feel different but I guess our lives will never be the same.
Sheldon: I don't know. We're going to work like always. I still put my pants on both legs at a time.
Amy: One day, that's going to end very badly.

Sheldon: You know, when you think about it, now that we're Nobel Prize winners, our names will be linked together forever.
Amy: We're married. Our names are already linked together forever.
Sheldon: Oh please! That's just a piece of paper. This is a piece of paper and a medal.

Sheldon: How's it feel to be married to a Noble Prize winner?
Amy: You tell me.
Sheldon: Oh, Amy-centric! What a fun way to look at it.

You have your whole life to smack him around. This is MY time!

Leonard

Penny: Should we wake him up?
Leonard: Well, he did say if he fell asleep we were allowed to slap him awake.
Penny: Oh boy!

Sheldon: The only drug I need is the endorphins pumping through my brain in anticipation of our victory.
Amy: Well, technically, anticipation wouldn't be mediated by endorphins as much as dopamine but, y'know, you've been up all night so I'll give you that one.

Penny: Leonard? Coffee?
Leonard: Black and strong like Luke Cage.
Penny: I'm too tired to even be disturbed by that.

Penny: Okay let's try this. Think of yourself as one of those limited edition toys people like to collect.
Sheldon: I already do.

Penny: Come on, looks don't matter to Sheldon. [pause] Because he only has eyes for you!
Amy: Nice try.
Penny: Thanks, I was scrambling.

TBBT Quotes

It's very simple. Scissors cuts paper, paper covers rock, rock crushes lizard, lizard poisons Spock, Spock smashes scissors, scissors decapitates lizard, lizard eats paper, paper disproves Spock, Spock vaporizes rock, and, as it always has, rock crushes scissors

Sheldon

Leonard: Hi. I'm Leonard. You are beautiful. You pop, sparkle and buzz electric. I'm going to pick you up at eight, show you a night you will never forget.
Raj: Where are we going?