Boldly go, Howard Wolowitz.

Sheldon

Bernadette: I love that man.
Raj: Me too.

Howard's mother: Speak up!
Howard: From now on she's the only woman who can yell at me!

Would you like some aloe vera? You just got burned.

Sheldon

Bernadette's father: Here ya go.
Bernadette: Here ya go? What am I? A football?
Bernadette's father: Like that guy could catch a football.

Howard: There's fuel leaking and we're still gonna go?
Cosmonaut: Don't lose your Fruit Loops, Fruit Loops.

Sheldon: I'll do it provided I can perform the service in Klingon.
Bernadette: No.
Sheldon: What do you see in her?

Oh my gosh. I can't believe my maid of honor dress will be on Google Earth.

Amy

Sheldon: He asked her during coitus.
Howard: Did he get down on one knee or were you already there?

Leonard: Come on, Sheldon. It will be fun.
Sheldon: That's what you said about the Green Lantern movie. You were 114 minutes of wrong.

No! When I eat Fruit Loops the other astronauts make fun of me.

Howard

Actually, Fruit Loops just got married ... to a girl.

Cosmonaut

The Big Bang Theory Season 5 Quotes

You can't blame yourself. When your prefrontal cortex fails to make you happy promiscuity rewards you with the needed flood of dopamine. We, neurobiologists, refer to this as the skank reflex.

Amy

I feel like two totally different people. Dr. Jekyyl and Mrs. Whore.

Penny