Andrea: They take all the mirrors out of your house or something? You don't look good.
Cathy: Thank you! Finally someone telling me the truth.

I can't see you as a patient, Cathy. Because I don't see you as a patient.

Todd

With all the educated cock I've had it my mouth, it's cruel irony that my baby daddy is a bipolar dropout.

Rebecca

From now on, I am fighting for my life, not yours. You, my brother, can suck it and fuck it.

Cathy

No wonder you got cancer, Cathy. You're so full of lies and evil, you gave it to yourself.

Sean

Rebecca: You will be my first real friend with cancer. I will be forever changed.
Cathy: Hopefully for the better.

Paul: He's been aggressively farting.
Therapist: Was anyone hurt?

It's not true what they say about offing yourself. It's a little red tape, but no big thing.

Marlene [on heaven]

I have a very stubborn cancer!

Cathy

Sean to Cathy]: No matter how repulsed by you I am, you can't deny our biological bond.

Cathy: You know, you can't hate black people, right?
Marlene: I don't. I just need to get angry sometimes.

You're the yin to my yang, the ping to my pong, the normal to my crazy. Let's be us together.

Paul

The Big C Quotes

Sean: The last you could do is buy a damn Hybrid.
Cathy: The least you could do is take a shower.

Paul: Can we at least figure out what to tell Adam? Because right now, my story is: "Adam, your mom's a meanie!"