Fallout Boy: Gee, Radioactive Man. When can I smoke Laramies?
Radioactive Man: (Laughs) Ahh, not until you're sixteen.

Homer: Mmmm... hors dourves.
Marge: Homer! You promised!
Homer: I promised I wouldn't eat? Never! You lie!

Go easy on the al-key-hole.

Marge

Marge: Oh, they're here. How does everything look?
Homer: Yeah, how do I look?
Marge: Do we have enough glasses?
Homer: Do we have enough gag ice cubes?
Marge: Homer, Homer, put a record on.
Homer: What are all our friends' names again?

Marge: Well I was thinking... do you think you could babysit the kids this weekend, I wouldn't ask, but we're desperate.
Grampa: Oh suuuure! Last resort. Old Grandpa the feeb. The guy who can't be counted on for nothing knowhow dag-nammit. Everyone's against me! (Pause) I'll do it!

Homer: Bart! Do that thing you do that's so cute!
Bart What?
Homer: That thing you know how to do!
Bart: What!?
Homer: Go to bed!

I like to think that I'm a patient, tolerant, woman and that there was no line you could ever cross that would make me stop loving you. But last night you didn't just cross that line, you threw up on it!

Marge

Lovejoy: Come on Homer what are her faults?
Homer: Well sometimes she can be annoying!
Marge: Oh Homer.
Lovejoy: Now Marge, don't interrupt, you'll get your turn.
Homer: I'm done.
Lovejoy: Okay, Marge.
Marge: Well its not that I don't love the guy, I'm always sticking up for him, it's just that he's so self-centered. He forgets birthdays, anniversaries, holidays. He chews with his mouth open, he gambles, he hangs out at a seedy bar with bums and low lifes.
Homer: Oh it's true!
Lovejoy: Homer don't interrupt.
Marge: He blows his nose on the towels and then puts them back in the middle!
Homer: I only did that a couple of times!

Reverend Lovejoy: Ned, Maude, what brings you here?
Ned: Well... sometimes God bless her, she underlines passages in my bible because she can't find hers!
Homer: Oh, lucky you don't keep guns in the house.
Reverend Lovejoy: Homer, why are you here?
Homer: Oh, because I got drunk and looked down her dress!

(Bart and Lisa's breakfast with Grampa)
Grampa: (Pours Lisa a cup of coffee) Sugar?
Lisa: (Nervous) Yes, ten please.
Bart: (Rattlin') Hey Grampa, top me off!
Grampa: Are you sure your Ma let you kids drink coffee?
Bart: FOR THE LAST TIME, YES!!!!

Mr. Bergstrom: Lisa, your homework is always so neat. How can I put this? Does your father help you with it?
Lisa: No. Homework's not my father's specialty.
Mr. Bergstrom: Well there's no shame in it, I mean, my dad ...
Lisa: Not mine.
Mr. Bergstrom: You didn't let me finish.
Lisa: Unless the next word was burp, you didn't have to.

Ralph: What's Lyme Disease?
Principal Skinner: I'll field that one. Lyme disease is spread by small parasites called ticks. When a diseased tick attaches itself to you, it begins sucking your blood. Malignant spirochetes infect your bloodstream, eventually spreading to your spinal fluid and on into the brain.
Miss Hoover: The Brain? Oh dear god!

The Simpsons Season 2 Quotes

Who would have thought that pushing a boy into the girls' lavatory could be such a thrill? The screams! The humiliation! The fact that it wasn't me! I've never felt so alive.

Martin

Bart: (prays) Well, old-timer, I guess this is the end of the road. I know I haven't always been a good kid, but if I have to go to school tomorrow, I'll fail the test and be held back. I just need one more day to study, Lord. I need your help.
Lisa: (spying on Bart) Prayer. The last refuge of a scoundrel.
Bart: A teachers' strike, a power failure, a blizzard. Anything that'll cancel school tomorrow. I know it's asking a lot, but if anyone can do it, You can. Thanking You in advance, Your pal, Bart Simpson.