IZZIE: "Well, how much did George tell you?"
MRS. O'MALLEY: "Everything. I'm his mother."
IZZIE: "Okay, then you know that Callie has a little bit out there. I mean I have seen more of that girl's body than I have with my own and she's a little too much information for me. I mean nobody needs to be naked that often... He didn't tell you that? Um, I dunno why they broke up. George seemed to really like her and he kinda needed her. I mean, you remember the whole George and Meredith thing."
MR. O'MALLEY: "Wait! George and Meredith?"
MRS. O'MALLEY: "I knew it."
IZZIE: "George didn't tell you that either?"

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Izzie Stevens
Grey's Anatomy Season 3 Episode 9: "From a Whisper to a Scream"
Grey's Anatomy
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Grey's Anatomy Season 3 Episode 9 Quotes

DEREK: "Six-letter word for 'pinnacle.'"
MEREDITH: "Zenith."
DEREK: "Ah, this is good. No sex. Crossword puzzles. Current events. When does the knitting start?"
MEREDITH: "Shut up. Good things come to those who wait."
DEREK: "Yeah? I want sex."
MEREDITH: "There will be no sex."

[narrating] "As doctors, we know everybody's secrets. Their medical histories. Sexual histories. Confidential information that is as essential to a surgeon as a ten-blade, and every bit as dangerous. We keep secrets, we have to, but not all secrets can be kept."