Watch Grey's Anatomy Season 5 full episodes online, free and paid options via our partners and affiliates.

Izzie in the Afterlife?
Watch Grey's Anatomy Season 5 Episode 24
"Now or Never"
Original Air Date:

The fifth season concludes with George making a stunning announcement, Bailey questioning her pediatric fellowship program, and Izzie's fate hanging in the balance.

C. Torres
Watch Grey's Anatomy Season 5 Episode 23
"Here's to the Future"
Original Air Date:

The first of a two-part season finale finds Izzie fighting for her life as Mark and Owen contemplate their future relationships and careers.

What a Difference
Watch Grey's Anatomy Season 5 Episode 22
"What a Difference a Day Makes"
Original Air Date:

As Grey's Anatomy turns 100, Meredith and Derek prepare to walk down the aisle as Izzie's condition brings back familiar (handsome!) symptoms.

Mer Grey
Watch Grey's Anatomy Season 5 Episode 21
"No Good at Saying Sorry (One More Chance)"
Original Air Date:

As preparations continue for Meredith and Derek's wedding, her father returns to make amends. Izzie receives a visit from one of her estranged parents, as well.

Bailey and a Small Patient
Watch Grey's Anatomy Season 5 Episode 20
"Sweet Surrender"
Original Air Date:

Izzie plays wedding planner to take her mind off her treatment, while Callie introduces Arizona to her disapproving father, and Owen seeks help for his PTSD.

Hail to ...
Watch Grey's Anatomy Season 5 Episode 19
"Elevator Love Letter"
Original Air Date:

Derek returns to the OR after his meltdown, while Izzie's condition requires her to undergo an operation of her own.

Stand By Me
Watch Grey's Anatomy Season 5 Episode 18
"Stand By Me"
Original Air Date:

Cristina and Izzie debate what do to next, while Mer attempts to get Derek out of the woods and back to work.

Chief and Heir Apparent
Watch Grey's Anatomy Season 5 Episode 17
"I Will Follow You Into the Dark"
Original Air Date:

Derek decides to quit, but Meredith refuses to give up on him. Bailey and the Chief continue to bicker, while Izzie's interns discover something unsettling.

The Plight of Dr. Bailey
Watch Grey's Anatomy Season 5 Episode 16
"An Honest Mistake"
Original Air Date:

Derek and Addison square off yet again - this time with a patient's life in the balance. Bailey, meanwhile, is stunned by Richard's recommendation letter.

Watch Grey's Anatomy Season 5 Episode 15
"Before and After"
Original Air Date:

Addison, Naomi and Sam rush to Seattle Grace with Archer and reunite with old friends Derek and Mark. Izzie employs her fellow doctors in a medical game. Owen runs into someone from his past.

Mexie Love
Watch Grey's Anatomy Season 5 Episode 14
"Beat Your Heart Out"
Original Air Date:

In "Beat Your Heart Out," Derek searches for the best way to pop the question to our girl, while Little Grey wants to go public with Big Sloan.

And You Are?
Watch Grey's Anatomy Season 5 Episode 13
"Stairway to Heaven"
Original Air Date:

As a patient's condition becomes more and more dire, Bailey becomes more and more desperate to do something - anything - to save him.

Doctor Meredith Grey
Watch Grey's Anatomy Season 5 Episode 12
"Sympathy for the Devil"
Original Air Date:

Death row inmate William is still around and he's shaking things up, while Derek's mother comes to Seattle Grace and meets Meredith for the first time.

Wish You Were Here
Watch Grey's Anatomy Season 5 Episode 11
"Wish You Were Here"
Original Air Date:

Grey's Anatomy returns from its holiday hiatus with its 11th episode of Season Five.

Dr. Dixon
Watch Grey's Anatomy Season 5 Episode 10
"All By Myself"
Original Air Date:

Dr. Yang is forced to give up the coveted solo surgery, while sparks between Mark and Lexie possibly heat up.

Watch Grey's Anatomy Season 5 Episode 9
"In the Midnight Hour"
Original Air Date:

Why the heck are the interns cutting themselves? And why the heck is Izzie still seeing Denny? And what happens when it all goes wrong?

A Lexie Grey Photo
Watch Grey's Anatomy Season 5 Episode 8
"These Ties That Bind"
Original Air Date:

As if this season weren't turbulent enough, it's time for a couple of newcomers - Harriet Dixon and intern Sadie - to make their debuts and shake things up at Seattle Grace.

Watch Grey's Anatomy Season 5 Episode 7
"Rise Up"
Original Air Date:

The sudden revelation that this is Brooke Smith's (Erica Hahn) last episode has dominated the discussion and speculation of this episode so far.

Life During Wartime
Watch Grey's Anatomy Season 5 Episode 5
"Life During Wartime"
Original Air Date:

Empowered by the Chief, Bailey has new responsibility and the new head of trauma - Owen Hunt - is shaking things up at Seattle Grace.

Bailey Photo
Watch Grey's Anatomy Season 5 Episode 4
"There's No 'I' in Team"
Original Air Date:

Mark talks with Callie about love. Seriously. Bailey heads a risky surgery - even by Seattle Grace standards. Derek gets sole credit for a tumor study he and Mer did.

Derek, Izzie
Watch Grey's Anatomy Season 5 Episode 3
"Brave New World"
Original Air Date:

Meredith freaks when Derek discovers her mother's diary, Callie preps for a date with Erica, and Cristina stumbles into a new part of the hospital.

Chief in Charge
Watch Grey's Anatomy Season 5 Episode 2
"Here Comes the Flood"
Original Air Date:

In case the title didn't give it away, Seattle Grace is hit by a flood in this episode. Or more accurately, a plumbing fiasco.

Izzie to the Rescue
Watch Grey's Anatomy Season 5 Episode 1
"Dream a Little Dream of Me"
Original Air Date:

Meredith and Derek soon discover that 'happily ever after' isn't that easy, a military doctor, Dr. Owen Hunt, catches Cristina's eye, an...

Grey's Anatomy Season 5 Quotes

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)

Derek: I wanna be with you forever, and you wanna be with me forever. In order to do that we need to make vows. A commitment. A contract. Give me a piece of paper.
Meredith: I don't! I... I... I don't. I have post its!
Derek: (takes the post its and a pen) Ok. What do we wanna promise each other?
Meredith: That you'll love me... even when you hate me.
Derek: To love each other, even when we hate each other. (writes it down) No running. Ever! (Mer smiles and comes and sits in front of him) Nobody walks out. No matter what happens.
Meredith: No running.
Derek: (writes it down) What else?
Meredith: That we'll take care of each other, even when we're old, and smelly, and senile. And... if I get Alzheimer's and forget you...
Derek: I will remind you who I am, every day. To take care when old, senile, and smelly (writes it down) This is forever. (signs it) Sign.
Meredith: This is our wedding. A post it? (smiles)
Derek: Mhmmm. If you sign it.
Meredith: (signs it, and hands it back. Has tears in her eyes) Now what?
Derek: Now I kiss the bride. (They kiss)
Meredith: (smiling) Married.
Derek: (smiling) Married. (sticks their post it in Mer's locker) You see that? (Mer nods and smiles) Plenty of time.