Alexis Bledel - Gilmore Girls
This one is one of the most surprising. Since she was cast in a failed Fox comedy, she's been very under the radar, but she has solace in knowing that her sole hit is returning for another go around.
Alison Mack - Smallville
Smallville was a big show for The WB and The CW, but Mack decided to bid adieu to it before the show signed off. 11 seasons would be a long time to stick with any show, but she's not had much traction in any role since and her mose recent dud was American Odyssey.
Nicholas Brendon - Buffy The Vampire Slayer
Buffy's BFF failed to stay relevant after Buffy concluded in 2003 and his only notable role since was in Private Practice, but that was just for a handful of episodes.
Ian Ziering - Beverly Hills, 90210
He was part of a genre defining drama that lasted many seasons, but now he's only known for Sharknado. This ones a head scratcher.
Patricia Arquette - Medium
Arquette captivated audiences worldwide as a medium, but she's currently in CSI: Cyber which is one of the worst shows on the air and is far from a hit!
James Van Der Beek - Dawson's Creek
James is also starring in CSI: Cyber. Perhaps it was part of the casting call that they were seeking TV one hit wonders.