Emily Thorne - Revenge
Jack and Emily (Amanda) were childhood best friends who were separated for some pretty complicated reasons. Their feelings for each other were obvious since Season 1, and they end up married at the end of the show.
Corry Matthews - Boy Meets World
Topanga is Cory's childhood friend who he eventually falls for. They do have a bit of an off/on relationship, but they get married in the show's final season.
Luke Danes - Gilmore Girls
Luke was always crushing on Lorelai. He even kept a memento from the first time they met and held onto it for years. Although they were just friends for a while, they ended up happily married.
Jim Halpert - The Office
There was never a time on The Office that Jim wasn't head over heels in love with Pam. He bought a ring the first week they started dating, and even admitted to wanting to marry her pretty much the day he met her.
J.D. - Scrubs
Elliot is the first girl J.D. is romantically interested in on Scrubs. Their relationship is complicated and full of many twists and turns, but when all was said and done they ended up together.
Tate Langdon - American Horror Story
Violet was Tate's only love that we know of, but it doesn't change the fact that he vowed to wait forever for her forgiveness, which he eventually got. As of Season 8, the two are back together and will probably stay that way since the special episode served as an ending to their story.