She will be in for the fight of her life, and her own mother-in-law appears to be immediately on the side of the enemy if the first look at the season is any indication.
"Scotland's Queen will fall." Those words aren't from the mouth of Queen Elizabeth, but from someone Mary once trusted. Just who is it that is so certain Queen Mary is on her way out?
Take a look at the trailer and be sure to tune into Reign on its new night when it premieres on Friday, Oct. 9.