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In this preview for "In the Midnight Hour," from the fifth season of Grey's Anatomy, the residents vie for the big solo operation.

A preview for "In the Midnight Hour," from the fifth season of Grey's Anatomy. Meredith and Cristina try to rescue Lexie & Co. from an imminent disaster.

A slightly different promo for Episode Nine of Season Five of Grey's Anatomy, entitled "In the Midnight Hour."

A promo for Episode Nine of Season Five of Grey's Anatomy, entitled "In the Midnight Hour."

In this clip from "These Ties That Bind," Cristina apologizes to Owen. Then they kiss, obviously.

In this clip from "These Ties That Bind," Izzie has an interesting encounter in the bedroom. It's not what it sounds like.

In this clip from "These Ties That Bind," Cristina asks Callie what happened to Erica and Callie breaks down.

On the third episode of the 20th season (!) of The Simpsons, Bart somehow changes roles with another man and as he arrives at his new home (among McMansions) he catches a brief glimpse of our very own McDreamy and McSteamy ... animated of course.

Sadie arrives and Meredith is happy to see her. Derek and Cristina lament that this supposed close friend of hers is here.

Derek confronts Owen about a patient, then pleads with Callie for help.

Guest star Mary McDonnell plays Dr. Harriet Dixon, a renowned cardiac surgeon who suffers from Asperger's syndrome.

Bailey tells Dr. Dixon about the transplant patient ... and she puts Alex in his place for his terminology.