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Sam
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Ok so a fan on Ask Ausiello asked whether we would ever see closure between Alex and Izzie. His reply was, the latest is in Entertainment Weekly, and its juicy... What do you think, could Katherine return? Or should Alex find closure in the arms of another. It would ne good if she came back and he had found closure with someone else...Shonds also ruled out an Alex/Lexie/April triangle, but I don't think that rules out possible singular hookups, Alex/April or Lexie/Alex... And for Calzona fans, she said that they were in it for the long haul? so I am guessing Arizona'a trip to Africa won't keep them apart! Speculate, people...
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Danielle
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Alex and April is just laughable, not to mention highly unlikely. I would look for Alex to get closure by going to see Izzie. That doesn't require KH as they don't even have to show him talking to her. They just have to have him talk about it. I also don't think closure is going to come in the traditional sense that he lets her go. I have a feeling the letting go will be of the past and they will have an off screen relationship. JMO 

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MaxieForEver
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i don't think Alex and Lexie will ever get back together. She'll someday be back together with Mark. You just don't know when ;)

But Alex/April ... why not? i like her and i like him. Maybe they're good together (:

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Crystal Adrienne Wilson
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I would LOVE to see Izzie back for one....not only for closure with Alex, but also because I loved her character! Alex and Iz never made a good couple anyway, it should have just been a hook up. He is the type of guy who just can't settle down. I would also like seeing Lexie and Mark back together...very cute.

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Grey's Anatomy Quotes

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)

There's a reason I said I'd be happy alone. It wasn't 'cause I thought I'd be happy alone. It was because I thought if I loved someone and then it fell apart, I might not make it. It's easier to be alone, because what if you learn that you need love and you don't have it? What if you like it and lean on it? What if you shape your life around it and then it falls apart? Can you even survive that kind of pain? Losing love is like organ damage. It's like dying. The only difference is death ends. This? It could go on forever.

Meredith
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