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My favorite seasons were seasons 2 and 4 because of MerDer drama.  I find their history the most propelling and interesting.  Honestly, season 1 was fine but I felt like the first couple episodes of season 1 was like the first day at school (dreadful memories).  And season 6 is O.K. but with Meredith taking the break (RL baby, episode - giving liver transplant to father) kind of ruined this season for me.  That MerDer drama is what I find to be in the top 3 appeals of the series for me.  Although season 2 and 4 were excellent because Meredith and Derek are constantly fighting.

As for Izzie and Alex, I always hated Alex's character.  I just don't like his "vibe" I guess.  Katherine Heigl is amazing though.   And I dislike the whole Iraq PTSD ideology behind Owen's character.  I feel like it's overrated because of the negativity brought by the war this past decade.

I hope that April chick goes crazy and puts Derek or Meredith in a life or death situation.  I would rather have Meredith the one close to death because Patrick Dempsey did an amazing job performing grief renactment during the "Drowning on Dry Land" 3-part episodes.

Ellen Pompeo better not take another break though or I'm going to be pissed!  Swear that ruined a lot of season 6 for me.

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Grey's Anatomy Quotes

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)

There's a reason I said I'd be happy alone. It wasn't 'cause I thought I'd be happy alone. It was because I thought if I loved someone and then it fell apart, I might not make it. It's easier to be alone, because what if you learn that you need love and you don't have it? What if you like it and lean on it? What if you shape your life around it and then it falls apart? Can you even survive that kind of pain? Losing love is like organ damage. It's like dying. The only difference is death ends. This? It could go on forever.

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