Grey's Anatomy Spoilers From Kevin McKidd, James Pickens, Jr.

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The Chief of Surgery at Seattle Grace, Dr. Richard Webber, and the Head of Trauma, Dr. Owen Hunt, are both profoundly affected by the death of their colleague, Dr. George O'Malley, on the upcoming sixth season of ABC's Grey's Anatomy. How could they not be?

How will the doctors respond to the departure of George (who was played by the disaffected T.R. Knight)? The actors themselves shed some light on this subject, as well as what we can expect with respect to their characters' personal lives, starting this September.

Follow the links below for interviews with:

I'm Sorry Moment

Steve Marsi is the Managing Editor of TV Fanatic. Follow him on Google+ or email him here.

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Grey's Anatomy Quotes

There's a reason I said I'd be happy alone. It wasn't 'cause I thought I'd be happy alone. It was because I thought if I loved someone and then it fell apart, I might not make it. It's easier to be alone, because what if you learn that you need love and you don't have it? What if you like it and lean on it? What if you shape your life around it and then it falls apart? Can you even survive that kind of pain? Losing love is like organ damage. It's like dying. The only difference is death ends. This? It could go on forever.


MEREDITH: "You don't get to call me a whore. When I met you, I thought I had found the person that I was going to spend the rest of my life with. I was done! All the boys and all the bars and all the obvious daddy issues, who cares? I was done. You left me. You chose Addison. I'm all glued back together now. I make no apologies for how I chose to repair what you broke. You don't get to call me a whore."
DEREK: "This thing with us is finished. It's over."
MEREDITH: "Finally."
DEREK: "Yeah, it's done."
MEREDITH: "It is done."