McSobby

McSobby

Derek is inconsolable at the thought of losing Meredith.
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She has Cooties

She has Cooties

This is awkward
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Man With the Hair

Man With the Hair

Derek's hair is a natural wonder.
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Flip You For Her?

Flip You For Her?

McDreamy and McVet at the prom.
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Pole Position

Pole Position

Derek takes Cristina fishing to get away from it all on Grey's Anatomy. How that plays out will be fun to watch.
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Posing For a Photo

Posing For a Photo

That's what it looks like, anyway. Get ready for Seattle Grace: The Documentary.
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Taking Some Time Away

Taking Some Time Away

Cristina and Derek go fishing. Now that's going to be worth watching.
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Brain Surgery

Brain Surgery

In this scene from "The Becoming," from the fourth season of Grey's Anatomy, Dr. Meredith Grey prepares for an operation in her clinical trial with Derek. But what she's really thinking about is something altogether different.
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Former Spouses

Former Spouses

A promotional photo from the May 1, 2008 episode of Grey's Anatomy, entitled "Piece of My Heart." Dr. Addison Montgomery (Kate Walsh) and Dr. Derek Shepherd (Patrick Dempsey) share a lighter moment. They used to be married, can you believe it?
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Dailey

Dailey

We love Derek and Bailey together. Not in a romantic way, but their scenes together always kill. Don't you agree?
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Addek Reunion

Addek Reunion

Not a real romantic reunion, of course (and thankfully) - but Addison and Derek are back together on Grey's Anatomy at least for one week, sparring over surgery.
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Derek and George Joke

Derek and George Joke

McDreamy and the Intern chat it up.
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Grey's Anatomy Quotes

MEREDITH: "You don't get to call me a whore. When I met you, I thought I had found the person that I was going to spend the rest of my life with. I was done! All the boys and all the bars and all the obvious daddy issues, who cares? I was done. You left me. You chose Addison. I'm all glued back together now. I make no apologies for how I chose to repair what you broke. You don't get to call me a whore."
DEREK: "This thing with us is finished. It's over."
MEREDITH: "Finally."
DEREK: "Yeah, it's done."
MEREDITH: "It is done."

There's a reason I said I'd be happy alone. It wasn't 'cause I thought I'd be happy alone. It was because I thought if I loved someone and then it fell apart, I might not make it. It's easier to be alone, because what if you learn that you need love and you don't have it? What if you like it and lean on it? What if you shape your life around it and then it falls apart? Can you even survive that kind of pain? Losing love is like organ damage. It's like dying. The only difference is death ends. This? It could go on forever.

Meredith