New Englander

Patrick Dempsey looks every bit the classic New Englander he is in this photo from Entertainment Weekly in the fall of 2007. The Grey's Anatomy star never ceases to amaze.
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Easy Rider

Patrick Dempsey is a smooth operator, and is seen here in his Entertainment Weekly photo shoot from October 2007. The handsome Grey's Anatomy star is amazing each and every time we see him.
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Black and White Patrick

The amazing Patrick Dempsey from his exclusive Entertainment Weekly photo shoot in October 2007. The handsome Grey's Anatomy actor is just so McDreamy.... no one can deny it.
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Patrick on the Stairs

Patrick Dempsey from his Entertainment Weekly photo shoot in October 2007. The handsome Grey's Anatomy star is just so McDreamy. Even when sitting on the stairs!
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Residents Square Off

Alex and Miranda talk about the latest case. Karev is taking on a bigger and bigger role of late.
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A Grey Matter

Lexie Grey and her estranged older sister Meredith Grey talk about some things. This family drama promises to take over their lives in and outside the hospital in Season Four.
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Another Medical Mystery

They just keep coming to Seattle Grace Hospital, and Alex Karev seems to be in the middle of a lot of them.
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Karev is All Over it

Alex Karev is a big resident at Seattle Grace now, and he has not hesitated to make his presence felt. It will be interesting to see this guy develop this season.
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Sexy Lexie

Lexie Grey is a cutie... although it's unclear whether she will become romantically involved with anyone at the hospital. Who, if anyone, will it be?
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Buttin' Heads

Alex Karev (Justin Chambers) gives Miranda Bailey (Chandra Wilson) his trademark disgruntled stare. Will these residents clash in "Let the Truth Sting" ?
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Season 4 Cast at Press Conference

Patrick Dempsey, Ellen Pompeo and seven of their fellow cast members pose for the cameras at a September 27 press conference for Grey's Anatomy. Missing are Chyler Leigh and Katherine Heigl.
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Love, Addiction

That's what the relationship is for these two. But will it end well for Mer and Der?
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Grey's Anatomy Quotes

COOPER: "It's wrong?"
NAOMI: "You need to meet a grown up. You need to date someone your own age."
VIOLET: "Someone without a porny internet name and perhaps no criminal past."
NAOMI: "A nice girl."
VIOLET: "A reliable girl."
NAOMI: "Someone who you can have a relationship with."
VIOLET: "You’re a respected doctor."
NAOMI: "Go out in the real world. Meet a woman your own age and go out."
VIOLET: "Be a man."

ADDISON: "You work with your ex-husband in a shrine for your ex-husband."
NAOMI: "It’s actually a good book. And we're friends. And we stayed friends after we divorced. It’s very healthy. We're healthy."
ADDISON: "What happened between you and Sam?"
NAOMI: "Addison, you and I were close in med school, but it was a long time ago."
ADDISON: "Oh, Naomi. Come on. You can’t stay mad at me forever. I know you."