DeLuca may be wondering what has brought his sister all the way from Italy to GSM because it can't possibly be just to visit her charming brother. Siblings always have ulterior motives. Will he be the person behind his sister making a startling new discovery?
Amelia may have made a break in her case and she's ready to take it head on. Can she save her patient in time? Probably, she appears competent and ready for action.
Is Maggie part of the team of doctors helping Megan? It's always good to have a child prodigy on the case. What if she's working with DeLuca's sister instead? That could certainly make things interesting given her history with DeLuca.