Observation Room

Foreman, House and Thirteen observe as a patient undergoes a highly experimental surgery. That's pretty much the status quo each week.
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Under My Skin Photo

Does House look more tired than usual? He hasn't slept in days during this scene from "Under My Skin."
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Asleep!

House is having major sleep issues in the episode "Under My Skin." Cuddy to the rescue!
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You're Getting Sleepy

Cuddy tries to help House fall asleep. We have a few idea of how she could accomplish this.
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A Thorough Exam

In "Under My Skin," Wilson examined his BFF. House is having a lot of trouble sleeping.
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Insomniac Pic

As House's fifth season winds down, the doctor has more and more trouble sleeping. Visions of Amber will do that to anyone.
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House Season 5 Episode 23 Quotes

So, you're saying... you want a prenup. In liquid form.

Dr. Chase (to Cameron)

Dr. Wilson: The door was closed for a reason.
House: Well, now it's opened for a reason. We need to talk.
Patient: He just told me I have kidney cancer.
House: Then you obviously need a moment to process.