Derek's a tumor junkie!

Meredith

Meredith: Are you two talking yet or just having sex?
Cristina: Not just sex. Hot, dirty, stand on my head sex.

Wearing the vagina squad scrubs in public? We have standards, Mer.

Cristina

Can you go have sex with him so he'll be nicer?

Lexie

So, I'm a tumor mule?

Lexie

Elena: I know who you really are, better than anyone, Stefan. I am not giving up.
Stefan: Elena, do you have any idea how pathetic that makes you?
Elena : No, Stefan. It makes me strong.

Caroline: You have to earn the over-nighter.
Tyler: I consider that a challenge.

Everything I like about me, is you.

Tyler [to Caroline]

Tyler: How did I get here?
Caroline: I brought you here. You were being a major d-bag.

Oh, they don't always get to ride the roller coaster. Sometimes they only get to spin the teacups.

Penny

Yes, Penny has a lot of money tied up in promiscuity futures.

Sheldon

Matt's trying to resurrect his dead sister! I think I'll go deal with that instead.

Bonnie