Money like that changes people.

Charlie

He wants you to keep your nose out of his business so he takes your nose.

Jim

Eli: I wouldn't rule off the daughter.
Melinda: She's fifteen.
Eli: Even better.

I love angry teenagers.

Eli

Dean: And the Enochian exorcism?
Castiel: Fake. It actually means, "You, um, breed with the mouth of a goat." It's funnier in Enochian.

Castiel: This creature has the power to take a human's form, read minds. Book of Revelations call her the "Whore of Babylon."
Dean: Well, that's catchy.

Sam: What's wrong with you? Are you... drunk?
Castiel: No! Yes.
Sam: What the hell happened to you.
Castiel: I found a liquor store.
Sam: And?
Castiel: I drank it.

Dean: 'Course, that's if you can get past the velvet rope. Must be nice--being chosen.
Leah: Well, Dean... you're chosen.
Dean: More like cursed.

No drinking, no gambling, no pre-marital sex. Dean, they basically just outlawed 90% of your personality.

Sam

I'm going to work my magic and we're both going to be here on Day 22 and 23.

Sandra (to Courtney)

I'm determined little bitch and I'll put up with a lot of crap.

Courtney

I'm the poster child for weak survivor.

Courtney