The game. They say a person either has what it takes to play or they don't. My mother was one of the greats. Me on the other hand. I'm kinda screwed.

Meredith

[narrating] "I can't think of a single reason why I should be a surgeon, but I can think of a thousand reasons why I should quit. They make it hard on purpose. There are lives in our hands. There comes a moment when it's more than just a game, and you either take that step forward or turn around and walk away. I could quit, but here's the thing. I love the playing field."

MEREDITH

CRISTINA: "You should get some sleep, you look like crap."
MEREDITH: "I look better than you."
CRISTINA: "That’s not possible."

MEREDITH: "We should forget it ever happened."
DEREK: "What? You sleeping with me last night? Or you throwing me out this morning? 'Cause both are fond memories I'd like to hang on to."
MEREDITH: "No, there will be no more memories. I'm not the girl in the bar anymore and you're not the guy. This can't exist. You get that, right?"
DEREK: "You took advantage of me and now you want to forget it?"
MEREDITH: "I did not take-"
DEREK: "I was drunk vulnerable and good looking and you took advantage."
MEREDITH: "Okay. I was the one who was drunk and you are not that good looking."
DEREK: "Maybe not today, but last night I was very good looking. I had on my red shirt, my good-looking shirt, and you took advantage."
MEREDITH: "I did not!"
DEREK: "Would you like to take advantage again, say Friday night?"

"The only person that can keep a promise that big is God, and I haven't seen him holding a scalpel lately."

PRESTON

MEREDITH: "Did you let me scrub in for this operation because I slept with you?"
DEREK: "Yes. Just kidding."

CRISTINA: [about George] "Total 007."
IZZIE: "007? What's 007?"
MEREDITH: "Licensed to kill."

GEORGE: "007. They're calling me 007, aren't they?"
MEREDITH: "No one's calling you 007."
GEORGE: "I was on the elevator and Murphy whispered 007."
CRISTINA: "Okay, how many times are we going to go through this, George? Five, ten? Give me a number or else I'm going to hit you."
GEORGE: "Murphy whispered 007 and everyone laughed."
IZZIE: "He wasn't talking about you."
GEORGE: "Are you sure?"
MEREDITH: "Would we lie to you?"
GEORGE: "Yes."

CRISTINA: "You know... don't be, don't do me any... don't do me any favors, its fine."
MEREDITH: "Cristina-"
CRISTINA: "You know what, you did a cut-throat thing, deal with it. Don't come to me for absolution. You want to be a shark, be a shark."
MEREDITH: "I'm not!"
CRISTINA: "Oh, oh, oh, yes you are. Only it makes you feel bad in your warm, gooey places."

CRISTINA: "Katie competes in beauty pageants."
DEREK: "I know that, but we have to save her life anyway."

MEREDITH: [about Derek] "You can't make a face, comment, or react in any way. We had sex."
CRISTINA: [about patient] "What about an aneurysm?"
MEREDITH: "No blood in the CT."
CRISTINA: "No drug use. No pregnancy. No trauma. Was he good? He looks like he’d be good. Was he any good?"

"If I hadn't taken the Hippocratic Oath, I would Kevorkian her with my bare hands."

MEREDITH

Grey's Anatomy Season 1 Episode 1 Quotes

MEREDITH: [to Derek] "Stop looking at me like that, like you've seen me naked."
DEREK: [smiles]

IZZIE: "Hi! I'm Isobel Stevens, but everyone just calls me Izzie."
MIRANDA: "I have five rules. Memorize them. Rule number one, don't bother sucking up. I already hate you, that's not gonna change."