GEORGE: "Who else did you invite?"
CRISTINA: "Izzie, we said the list was jocks only. Surgery, Trauma, Plastics. Who else?"
IZZIE: "Just some people from Peds."
CRISTINA: "You invited the preschoolers to Meredith’s house. The next thing you’ll say is you invited the shrinks."
IZZIE: [looks away]
CRISTINA [Izzie looks away]: "She invited mental defects. This party’s DOA."

[narrating] "Remember when you were a kid and your biggest worry was, like, if you'd get a bike for your birthday or if you'd get to eat cookies for breakfast. Being an adult? Totally overrated. I mean seriously, don't be fooled by all the hot shoes and the great sex and the no parents anywhere telling you what to do. Adulthood is responsibility. Responsibility, it really does suck. Really, really sucks. Adults have to be places and do things and earn a living and pay the rent. And if you're training to be a surgeon, holding a human heart in your hands, hello? Talk about responsibility. Kind of makes bikes and cookies look really, really good, doesn't it? The scariest part about responsibility? When you screw up and let it slip right through your fingers."


IZZIE: "Before, when you said, 'I am not your sister,' did you think I was emasculating you?"
GEORGE: "No. I'm too masculine to be emasculated."
IZZIE: "I'm sorry."
GEORGE: "Guess you put Dr. Model to rest?"
IZZIE: "Guess I did."

IZZIE: "What is your problem?"
MR. HUMPHREY: [to Izzie] "Look, I fantasized about you. About the woman in this photo, whoever she is. I'm not proud of it, but it's a fact. Do you know what they're gonna do to me today? I have cancer. And they're gonna lift up my legs and expose me to the world, and cut out my prostate, and my nerves. Effectively, neuter me. So is it so hard to understand that I don't want the woman who is in that photo to witness... my... my emasculation?"

[rips off her shirt, throws it at Alex] "Fine! Let's look at that tattoo up close and personal, shall we? What are these? Oh, my God! Breasts! How does anybody practice medicine hauling these things around? And what have we got back here? Let’s see if I remember my anatomy. Glutes, right? Let’s study them, shall we? Gather around and check out the booty that put Izzie Stevens through med school! Have you had enough, or should I continue, because I have a few more very interesting tattoos. You want to call me Dr. Model? That's fine. Just remember that while you're still sitting on two hundred grand of student loans... I'm out of debt."


IZZIE: [to Mer] "He didn't buy them."
MEREDITH [to George] "You didn't buy them?"
GEORGE: "Men don't buy tampons!"
IZZIE: [opens shower door, again] "You know what? You're gonna have to get over the whole man thing, George! We're women! We have vaginas! Get used to it!"
GEORGE: [on the bathtub floor] "I am not your sister!"

IZZIE: [in the bathroom] "Tampons, George, I just really needed some tampons!"
GEORGE: "I forgot when I got there."
IZZIE: [opens shower door] "No, you are so passive aggressive!"
GEORGE: "Naked! I am naked in the shower!"
IZZIE: [closes door] "Just tampons, George! I really needed tampons. God!"

IZZIE: "Here, my share of the grocery money. When are you going?"
GEORGE: "Tonight."
IZZIE: "Okay. Seriously, George. Please don't-"
GEORGE: "Yeah, could we not talk about it here?"
IZZIE: "What? Tampons?"
GEORGE: "Did you not hear a word I said?"
IZZIE: "You're a man, we know."
ALEX: "Talk about shrinking the salamander!"

DEREK: "What are our options?"
ALEX: "Brilliant! The guy's got nails in his head! Let's put him in a giant magnet."

MIRANDA: "You want to tell me what that was all about?"
IZZIE: "Nothing. He's probably just crazy or something... Bethany Whisper."
MIRANDA: "What?"
IZZIE: "Bethany Whisper. I did a new Bethany Whisper lingerie ad, he saw it in a magazine."
MIRANDA: "You had time to pose for magazines?"
IZZIE: "No, the shoot was last year, it just came out.
MIRANDA: "So, because he saw you in a thong..."
IZZIE: "No! It was not a thong!"
MIRANDA: "You're hiding out in the hallway?"
IZZIE: "I just think it might be easier if you assign another intern."
MIRANDA: "Easy is not in your job description. You are a doctor. He is a patient. He's your patient! Biopsy these! If they come back positive, I expect to see you in surgery. You're on this! You hear me? "

GEORGE: "There needs to be some rules."
MEREDITH: "So, what? So we can around in our underwear on alternate Tuesdays? Or you could see bras, but not panties? Or are you talking Amish rules? Because if you think you're gonna get Izzie to cover herself-"
GEORGE: "The amount of flesh exposed is not the point. You have to do something, it's your house."
MEREDITH: "It's my mother's house."
GEORGE: "Meredith!"
MEREDITH: "Do you like Izzie? Is that was this is about? You have a crush on Izzie?"
GEORGE: "Izzie? No! I don't like Izzie. No! She's not the one I'm attracted to."
MEREDITH: "Not the one. So there's a one?"

MR. HUMPHREY: [holding up magazine] "You don't need to do anything. Is this you? Is this you? It is, isn't it? You know what... go. Just... get out of my room."
IZZIE: "Mr. Humphrey-"
MR. HUMPHREY: "Get out of my room!"

Grey's Anatomy Season 1 Quotes

[narrating] "At some point, you have to make a decision. Boundaries don't keep other people out, they fence you in. Life is messy, that's how we're made. So you can waste your life drawing lines or you can live your life crossing them. But there are some lines that are way too dangerous to cross. Here's what I know. If you're willing to throw caution to the wind and take a chance, the view from the other side... is spectacular."


"If I miss a real procedure because of this case, they're gonna call me 007, because I killed you."