Mark Sloan never loses it in the ER. Not ever.

Addison

Turns out your stupid Post-It is 10 times the marriage my church wedding ever got to be. I'm moving on.

Alex

[to Mer] You gonna look me in the eye and tell me Derek never threw a cranionomy after the two of you spent an hour in the on-call room? Please.

Alex

I'm in the middle of a divorce. People call me the Nazi, and it's not because of my ice blue eyes. I spend 12 hours a day carving people up, and I like it. I have a child and I have no room for casual anything. I'm angry all the time. ... You want lunch, or you wanna show me the scan?

Bailey

[to Alex] Let me scrub in and I'll take you out to drinks afterwards and, you know...

Reed

Addison: You told her?
Mark: She's my kid. We were bonding.
Addison: That's now how you bond with children.
Mark: I'm still getting the hang of it.

[to Der] You wouldn't be starting a conversation about my personal life, would you? Bad idea? Bad idea!

Bailey

Addison: Let me say it once: Grandpa... Grandpa, grandpa, grandpa!
Mark: Okay. That was four times. Get it out of your system?

Get me Addison Montgomery!

Mark

Ask any physician and they can point to the one moment they became a surgeon.

Meredith

I'm a surgeon and I'm looking at a time bomb in a uterus. Shut it down now, Addison!

Mark

Mark: It's the guilt, you know? It's like every time I look at her... I just... The guilt is like a punch in the gut. Everyday.
Derek: Well, you shouldn't feel guilty, you didn't know.
Mark: I did know. I knew it when her mom got pregnant. She told me. I gave her a couple hundred bucks and I left town and I never saw her again. I figured she got an abortion. Hoped. But I did know.
Derek: Well you're a different guy now. You're not 18 anymore, you've grown up, and you're capable of better.

Grey's Anatomy Season 6 Quotes

Alex: What is this?
Izzie: Take off your pants.
Alex: Iz, it's a...
Izzie: Be my husband, get undressed, get into bed and hold me. I don't know what you're so mad about and I don't know what you're scared of because you won't talk to me. But, I'm scared too Alex. And I can't... if you won't... If we're gonna have any chance at a life together then I need you to. Please...
Alex: You died in my arms. You died in my arms! You freakin died, and then you left instructions that I wasn't allowed to save your life. You wanna know what I'm scared of? I'm scared of everything. I'm scared to move. I'm scared to breathe. I'm scared to touch you. I can't lose you. I won't survive. And that's your fault. You made me love you, you made me let you in. And then you freaking died in my arms.

Lexie: [narrating] Grief may be a thing we all have in common, but it looks different on everyone.
Mark: It isn't just death we have to grieve. It's life. It's loss. It's change.
Alex: And when we wonder why it has to suck so much sometimes, has to hurt so bad. The thing we gotta try to remember is that it can turn on a dime.
Izzie: That's how you stay alive. When it hurts so much you can't breathe, that's how you survive.
Derek: By remembering that one day, somehow, impossibly, you won't feel this way. It won't hurt this much.
Bailey: Grief comes in its own time for everyone, in its own way.
Owen: So the best we can do, the best anyone can do, is try for honesty.
Meredith: The really crappy thing, the very worst part of grief is that you can't control it.
Arizona: The best we can do is try to let ourselves feel it when it comes.
Callie: And let it go when we can.
Meredith: The very worst part is that the minute you think you're past it, it starts all over again.
Cristina: And always, every time, it takes your breath away.
Meredith: There are five stages of grief. They look different on all of us, but there are always five.
Alex: Denial.
Derek: Anger.
Bailey: Bargaining.
Lexie: Depression.
Richard: Acceptance.